Maintain a healthy diet that creates a daily calorie deficit. In order to lose any body fat, such as that found in your thighs, you must burn more calories than you consume or consume less calories! Aim to create a daily calorie deficit of 500 per day. Eat a low-fat diet that's rich in fiber to help lose the saddlebags and rid the body of some cellulite, though genetics determine how your body stores fat and produces cellulite. A high-fiber diet will cleanse toxins from your fat cells, reducing the bulging and dimpling affect that may appear on your saddlebags.