Anti-rheumatoid arthritis drug market of biological Speed - bio - pharmaceutical industries

Anti-rheumatoid arthritis drug market of biological Speed - bio - pharmaceutical industries

Non-steroidal anti-inflammatory drugs, steroids and anti-biological categories alleviate disease is rheumatoid arthritis, rheumatic drugs in the drug market, the rulers. The traditional biological class of anti-rheumatic drugs relieve symptoms only total Sell About 2% of the amount, but in 2008, the biology of anti-rheumatic drugs alleviate the disease accounts for at least 75% of sales.

Tips Of rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease, the global incidence rate of about 0.8%. Age of onset of this disease is 30 to 50 years old, it is estimated that for every 100,000 U.S. men and women respectively were 25, 54 with rheumatoid arthritis.

Recent years, people have recognized, for rheumatoid arthritis, the success of the treatment strategy of early, aggressive treatment, treatment to alleviate the disease by one or more anti-rheumatic drugs (DMARDs), especially non-steroidal anti-inflammatory drugs (NSAIDs) or corticosteroids, this approach can reduce the pain, the can relieve inflammation. Generation oral anti-rheumatic drugs alleviate the disease, methotrexate (MTX) remains the gold standard treatment of rheumatoid arthritis worldwide, and is used in most combined. However, the traditional anti-rheumatic drugs alleviate the disease, onset is slow, toxic, drug should be monitored, and the recent development of oral anti-rheumatic drugs alleviate the disease, leflunomide faster onset, 4 to 8 weeks The onset can be, and better compliance.

The past 20 years, the biology of anti-rheumatic drugs alleviate the disease began to emerge, these drugs with conventional anti-rheumatic drugs alleviate the disease compared to effect better, more secure, so that the drug General alone or in combination with methotrexate significantly improved patient outcomes. Especially for anti-TNF drugs, is becoming the biology of anti-rheumatic drugs alleviate the disease in those led, anti-tumor necrosis factor is a very important inflammatory mediators.

Currently on the market already has three of anti-TNF agents used to treat rheumatoid arthritis, this three medicines but also for the treatment of other immune inflammatory disease. 10 years ago by Johnson Company's CentocorOrtho biotechnology company and Schering-Plough Cooperation Special role in the development of anti-tumor necrosis factor monoclonal antibody drug infliximab (infliximab, Remicade), Amgen and Wyeth to develop the fusion protein drug etanercept (etanercept, Enbrel) has been approved for use on Treatment of Rheumatoid Arthritis. In 2002, for anti-TNF monoclonal antibody adalimumab (adalimumab, Humira) was approved for the treatment of rheumatoid arthritis.

Safe and effective cost is dispensable

The treatment of rheumatoid arthritis drugs have been such as safety, cost or efficacy of the restrictions. At present, the traditional anti-rheumatic drugs alleviate the disease has been Generic Listed, but similar side effects of these drugs limits their long-term use. The most common side effects include nausea, anemia, neutropenia, and increase the bruises, vomiting and diarrhea attack risk. In order to monitor the course of any possible drug toxicity and the prevention of liver fibrosis, also need regular liver function tests.

Although the anti-tumor necrosis factor inhibitors greatly increased the efficacy, but the cost of these drugs is very high. In the United States, patients receiving these drugs, the monthly cost of no less than 1,000. Although each type of biological anti-rheumatic drugs alleviate the disease has been providing different levels of discount, but the high cost of limiting these drugs in the United States and elsewhere to use. Long-term use of anti-tumor necrosis factor the safety issue has caused fears and become the focus of more research, especially such as tuberculosis, cancer and serious infection. However, the continually updated clinical data show that the benefits of these drugs than their toxicity and side effects, therefore, American College of Rheumatology is recommended to use these drugs.

POST COMMENT

Profit Bank by Millionaire Society Review and Coupon Discount Angular Chelitis Foundation Scam-Angular Chelitis Foundation Niche Profit Classroom - Review Xtreme Pip Poacher Scam-Xtreme Pip Poacher Blog Combat The Fat Program Scam Consoleunlock Rapidshare Scam Dealing Within the Foreign exchange market Driver Smith Review _Scam Easy Backup Wizard Torrent Free Scam Doggy Guide Scam Easy Stock Profits Scam Do You Know How To Talk To Your Email Marketing Lists? Video Marketing Tips For your products