A phenomenal week 2 of college football betting action begins with a key SEC showdown on ESPN as Mississippi State hosts Auburn at 7:30pm EST on ESPN
. Both teams are coming off impressive wins last week and online sportsbooks have opened with the Tigers -3. The key to this week 2 game may come down to the shaky Auburn defense being able to tighten up. Friday features an ESPN double header on the college football week 2 schedule starting with a huge intra-state match-up of Marshall hosting West Virginia at 7:00pm EST on ESPN. This will be the home debut of new coach Doc Holliday, who was a key assistant and recruiter for West Virginia before taking the job with the Thundering Herd. Holliday is hoping for a far better performance than the one he got last week in a blowout loss at Ohio State but the WVU is a Big East favorite and a 13-point favorite in college football odds.
The nightcap on Friday at 10:15pm EST on ESPN features a high powered Houston Cougar team hosting an up and down UTEP. Sportsbooks have opened with the Cougars -18 college football betting favorites at home. Saturday on the college football week 2 schedule will host many of games with BCS implications beginning with a host of games starting at 12:05pm EST. One of the most important key betting games of the entire year in the SEC as South Carolina hosts Georgia on ESPN2. Both teams are coming off impressive opening wins and are considered the prime challengers to Florida in the SEC East. Sportsbook have opened with the Gamecocks -2.5 favorites at home.
Florida will host South Florida at 12:25pm EST and will not be televised nationally, especially since the Gators were not impressive at all in their win last week over Miami-OH. The offense was sloppy and a far better effort will be needed against a USF team that is picked to contend for the Big East title. Many college football betting handicappers think that Florida might be an overlay as -16.5 favorites at "The Swamp". Iowa and Iowa State are coming off impressive wins and make for an important key betting game for the college football week 2 schedule at 3:35pm EST on ABC. Iowa is a Big Ten title contender but Iowa State is a dangerous, bowl minded team that could be a bargain as +13.5 underdogs.