Common Chinese and Western medicine interactions - Medicines, Medical - Pharmaceutical Industry

Common Chinese and Western medicine interactions - Medicines

, Medical - Pharmaceutical Industry

With the combination of Chinese and Western medicine work depth development of Sino-Western joint treatment of disease is also increasing, therefore, of Chinese and Western medicine combined with some of the issues have important clinical significance. 1 lower traditional Chinese medicine and western medicine side effects of western medicine Drynaria sexual warm, bitter taste characteristics, attending kidney, tinnitus; injection, while oral administration of streptomycin can reduce or eliminate Drynaria decoction of streptomycin on the 8th cranial nerve (vestibular ) toxicity. Spleen and kidney drugs (such as Radix) and chemotherapeutic drugs, can reduce the adverse effects of chemotherapy agents. 2 Chinese medicine and western medicine affect drug absorption excretion Chinese skullcap, woody, amomum, tangerine peel and so on intestinal significantly inhibited extended digoxin, vitamin B12, griseofulvin, etc. stay in the upper small intestine to increase drug absorption; absorption and strong Chinese medicine such as blood I can reduce carbon gastrointestinal absorption of oral drugs. 3 Chinese medicine and western medicine can play a synergistic role Such as licorice and hydrocortisone, cork and tetracycline, furazolidone, Polyporus, Alisma and Hydrochlorothiazide, furosemide combination may be synergistic; Citrus aurantium biliary sphincter relaxation can help celebrate Trappe factors into the biliary tract, anti-infection enhanced; Valley Amines with licorice, peony root, borneol combined treatment of peptic ulcer on the synergistic effect; Silver Flower with penicillin, dandelion is also a synergistic effect with co-trimoxazole. 4 Western incompatibility 4.1 containing tannin incompatibility of Chinese medicine and Western medicine chinensis, Terminalia, Burnet, pomegranate rind, cuspidatum, Woodwardia, Agrimony, Rhubarb, flat storage, jujube skin, holly leaf tablets, compound amaranth film, intestinal wind Huaijiao, intestinal pill, pill mole Shu, Qili San inclusive of a large number of tannins, (1) and amide bond or peptide bond with the structure of Western Compatibility: Tannins may have amide bond or peptide bond structure of proteins, generating strong hydrogen bond association complex and changing nature and role of the protein can precipitate from aqueous solution. Milk enzymes commonly used clinical health, trypsin, amylase, pepsin and other agents are protein preparations, such as Chinese medicine, and with tannins with services, will reduce the bioavailability of the enzyme preparation. (2) and preparation combined with heavy metal ions: a multi-phenolic tannins may be alkaline and some heavy metal ions and metal ion binding deposits formed. Clinical common calcium (calcium chloride, calcium lactate, calcium carbonate, calcium gluconate, calcium sugar, DING calcium); iron (ferrous sulfate, citric acid, ferrous fumarate and other man-made blood drug ), silicon carbon silver and cobalt chloride, and containing tannins, such as Chinese medicine with the service, can be combined with tannin salts precipitate formation, can not easily be absorbed. (3) tannins firm with the integration, both vitamin B1 can not be effective. For long-term use of Chinese medicine with tannins should be appropriate to add vitamin B1. (4) with tannin and preparation of Chinese medicine is not appropriate with tetracycline family of antibiotics and other antibiotics such as erythromycin, rifampin, griseofulvin, lincomycin, neomycin, chloramphenicol and ampicillin with the services. Can be combined with the services generated by tannin salt sediments can not easily be absorbed. (5) Chinese medicine containing tannins and alkaloids (berberine, quinine, strychnine) can be combined with the services generated tannic acid salt precipitates, can not easily be absorbed. (6) Dioscorea bulbifera, Terminalia, Galla, Sanguisorba and holly leaf and other herbs on the liver has some toxicity, and tetracycline, rifampin, chlorpromazine, isoniazid, and erythromycin and other drugs with liver toxicity in combination should be alert to drug-induced liver disease occurs.

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