Dermal Fillers: Know About Their History

Dermal Fillers are currently used to take away wrinkles by weakening the facial muscles

that pull and wrinkle the skin, but this toxin has a long and interesting history that goes back to the early 19th century. Discovered as a dangerous substance and used for therapeutic purposes, it was accidentally noticed to have cosmetic benefits as well.

In 1820, the earliest form of injectables was discovered by a Doctor Justinus Kerner who was investigating a food poisoning incident in Germany. It turned out that a food borne poison called botulism was responsible for the deaths of people eating sausage.

Dr. Kerner experimented with botulism and discovered many interesting things. The substance caused respiratory failure as well as droopy eyelids, which led the doctor to discover therapeutic effects. The toxin was capable of completely weakening any muscle tissue it came into contact with.

Doctor Emile Pierre van Ermengem discovered seven different forms of botulism in the 1890s and only three of those strains didn't make people ill. Although Dr. Ermengem discovered some harmless forms of botulism, the world became more interested in the dangerous strains for use as poisons, especially during World War II. In fact, Chinese spies planned a mission to assassinate Japanese Army leaders during the war, but it was never carried out.

During the 1960s, an ophthalmologist by the name of Alan B. Scott experimented with injecting monkeys with botulism to cure crossed eyes. This experiment proved successful and Doctor Scott moved on to testing on people to cure crossed eyes as well as facial ticks and vocal chord spasms.

In 1989, as the use of this beneficial substance to help people with these conditions increased, a company called Allergen purchased the right to distribute the botulism toxin and it was approved by the FDA a year later.

As use of this previously poisonous toxin continued, it was discovered to be a cure for excessive sweating and cerebral palsy. Dr. Jean Carruthers, an ophthalmologist, eventually noticed some of her patients experiencing a youthful and less wrinkled appearance as a side effect of the treatments.

By the mid 1990s, it was no longer used for corrective purposes as much as it was used for cosmetic purposes. In fact, supplies of this toxin almost ran out during the 1990s due to its popularity.

Although it took a long and circuitous journey, the dermal fillers have turned out to have a lot of benefits to make up for its poisonous origins. It may be hard to believe, but something as dangerous as a toxin can be turned to good uses.

by: Abigail Aaronson

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