Health Drug Guide: Summary Of Adverse Reactions Of Vitamin C
Health Drug Guide: Summary Of Adverse Reactions Of Vitamin C
Vitamin C Can accelerate the blood coagulation, stimulating hematopoietic function, and promote iron absorption in the intestines, and to lipids and increased the body's resistance to infection, and have to stop Cancer The role of substance nitrosamine formation. In addition to combat scurvy can be used for liver cirrhosis, acute hepatitis, and arsenic, mercury, lead, benzene poisoning and other chronic liver damage, and Keshan disease cardiogenic shock, have good effect, sometimes with large dose is more effective, so some people take large doses of vitamin C, that hurt. However, in recent years, according to research has shown that, due to increasing the amount of vitamin C increased, resulting in an increasing number of adverse reactions, it can not be taken lightly. Now its adverse reactions are presented below.
Diarrhea : Daily doses of 1-4 grams of vitamin C, can accelerate the small bowel, abdominal pain, diarrhea on sickness.
Gastric bleeding: a large number of long-term oral vitamin C, will be nausea, vomiting and so on. Meanwhile, due to increased gastric acid secretion, gastric and duodenal ulcer pain can facilitate intensification can lead to severe gastric mucosal hyperemia, edema, and cause stomach bleeding.
Stones: a lot of vitamin C into the human body, most of the decomposition by liver metabolism, metabolites from the urinary excretion of oxalic acid into oxalate. It was found that 4 grams daily of oral vitamin C, in 24 hours, urine oxalate levels will surge from 58 mg to 620 mg, if continue to take, oxalate, increasing the formation of urinary stones easily. In addition, vitamin C acidic, uric acid levels can increase, so will be awakened on the formation of stones in the role.
Anemia: long-term large doses of vitamin C, can reduce the intestinal Vitamin B 12 absorption, resulting in megaloblastic service of the poor condition aggravated. If the patient with congenital absence of 6 - phosphate dehydrogenase, the daily use of vitamin C more than 5 grams, it will promote red blood cell rupture occurred hemolysis, caused by anemia, severe cases and life course.
Gout: Purine metabolism in vivo is due to disorder caused by a disease, mainly for the high concentration of uric acid in the blood, resulting in joints, connective Organization Etc. a series of symptoms. The large doses of vitamin C, can cause dramatic increase in uric acid, induced gout.
Phlebitis: intravenous vitamin C, if too fast, can cause dizziness or syncope. Furthermore the drug on the vessel wall irritant, long used will produce phlebitis, or even blood clots.
Menstrual bleeding: abortion, women applied a lot of vitamin C, such as taking 6 grams a day, three days can cause menstrual bleeding.
Dependent infants: a large number of consecutive pregnant women take vitamin C, cause the fetus to the drug dependency. After birth, if a baby took a lot of vitamin C, scurvy may occur, if there lethargy, swollen bleeding gums, subcutaneous bleeding, and even the gastrointestinal tract, urinary tract bleeding and other symptoms.
Baby Digestion Bad: breast-feeding infants large doses of vitamin C, there may be anxiety, insomnia, indigestion embolism.
Children Orthopedics Disease: a large number of children taking vitamin C, can suffer from bone disease, and the incidence is higher.
Infertility: women of childbearing age take large doses of vitamin C (such as when the daily dose of more than 2 grams), would reduce fertility.
Immune Is reduced; long-term large doses of vitamin C, can reduce leukocyte phagocytosis, so that the body resistance to disease decreased.
Withdrawal reaction: large quantities of vitamin C, the blood drug concentration lower than normal, this is because the body is "overloaded", the change in the regulatory mechanism of the body to accelerate the decomposition of vitamin C and excretion . If suddenly disabled, the body will continue to maintain their metabolic rate, resulting in a lack of vitamin C led to scurvy. Therefore, withdrawal should be gradually reduced dose.
Allergic reaction: whether oral or intravenous vitamin C, for some people allergic reactions can occur, mainly as rash, nausea, vomiting, severe anaphylaxis can occur, it is not abused.
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