Monoclonal Antibody To Trf2 (ttaggg Repeat Binding Factor 2)

TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length (1)

. TRF2, like TRF1 contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes (1). TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini (2). The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells (2). Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types (3). TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length (1). TRF2, like TRF1 contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes (1). TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini (2). The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells (2). Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types (3). TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length (1). TRF2, like TRF1 contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes (1). TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini (2). The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells (2). Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types (3).

by: Stephen.Jones

POST COMMENT

Polyclonal Antibody To Parp The Holy Grail Body Transformation Review-How could a man can stand for again and again process of lose weight Excruciatingly Accurate Description of Gout Symptoms Uncovering Mesothelioma By Way Of Mesothelioma Symptom The Holy Grail Body Transformation Program Rapidshare-How could a man can stand for again and again process of lose weight Destroy Hemorrhoids Torrent Health Risks Tied In With Belly Fat How To Jump Higher For Free-Have a healthy and proper diet from the guide of The Jump Manual A Crash Course In Ordering Personalized Sweatshirts Excellent Info - Exercise To Improve Men'S Health How Soon Did You Become Pregnant After Taking Clomid? – Tips on how to Conceive and Give Birth to a Healthy Baby Use It or Lose It - Prostate Health The Holy Grail Body Transformation System-How could a man can stand for again and again process of lose weight