Old higher rate of adverse drug reactions - adverse reaction - the pharmaceutical industry sectors

Chinese medical profession that the drugs Adverse reactions The occurrence of a wide range

, from 10% to 30%, due to adverse drug reactions and hospital treatment of the total admissions to 3% to 7%, which accounted for death 0.596 ~ 0.9%. According to reports, China's annual adverse drug reactions due to hospitalization of patients up to 250 million, of which 50 million are serious reactions, at all levels in our patients in the hospital, some 20 million people die each year due to eating you adverse drug reactions, drug-induced deaths are the main infectious disease deaths in more than 10 times! resulting annual losses of up to 40 billion yuan. A survey in foreign countries, in the general hospital, the patient incidence of adverse drug reaction rate of 0.3% to 5.0%; hospitalized patients die of adverse drug reactions as much as 0.2% to 2.9%. Is generally believed that patients in hospital emergency 1% to 4% is caused by inappropriate medication; drug-induced deaths accounted for about 11% of the total number of inpatient deaths. Global non-accidental deaths, 1 / 7 died of irrational drug use, "adverse reactions, including medication errors and adverse interactions, is the sixth leading cause of death." 10% to 20% of patients prone to adverse drug reactions. Tolerance of the elderly and the drug significantly decreased the safety margin, so the higher the incidence of adverse drug reactions. According to statistics, the elderly, adverse drug reactions was 15.4%, the incidence of adverse drug reactions of 2 young people? 7 times. One study showed that 20 to 29 years age group adverse reaction rate of 3%, 51 to 60 age group was 14.3%, 61 to 70 age group is 15.7%, 71 to 80 age group was 18.3% 81 years old group was 24%. Meanwhile, the older the incidence of adverse drug reactions than younger people not only high, but once there, the extent than young men, or even death. Generally believed that, due to adverse drug reactions and hospital treatment and 1 / 3 (or 5% ~ 30%), drug-related death of 1 / 2 occurred in the age> 60 years old, indicating adverse drug reactions in elderly people of a more general adult even more serious. Abroad statistics also showed that hospitalized patients, adverse drug reactions is about 3%, and> 60 years of age accounted for 40%, occurred 15 times higher than the young group, according to U.S. data, there are 220 million people each year hospitalization due to adverse drug reactions, deaths of 10.6 million. Aged 20 to 29 years of age for the adverse reaction rate was 3%; 30 ~ 49 years the incidence was 7%; 50 ~ 69 years the incidence was 13%; 70? 79 years of age the incidence of increase than the 20 to 29 years old 7 times. Hunvifz statistics have reached the same conclusion, the elderly was significantly higher incidence of adverse reactions. 60 years of age was 6.3%,> 60 years of age to 15.4%. This may be related to the elderly organ gradually decline with age, liver and kidney dysfunction, the body regulating capacity and deterioration of the immune system, illness and more complicated medication, lack of clarity in the idea, which of drugs chance of adverse reactions. Vulnerable to adverse reactions Drugs Species Our report adverse drug reactions of drugs involved in many types of prescriptions under the 4793 statistics, the top few adverse reactions are; anti-TB drugs (8.2%) Antibiotic (5.8%), cardiovascular drugs (5.3%), residual urinary medicine, dehydration drug (4.3%), antibacterial inflammatory drugs (3.696), antipyretic and analgesic (1.3%). Topping the other statistics are: anti-microbial drugs (41.58%), cardiovascular system drugs (17.22%), nervous system drugs (10.71%), biological and biochemical products (5.48%), intravenous infusion and drugs ( 3.83%), anti-cancer drugs (3.19%) and antipyretics, anti-inflammatory pain medicine. prone to adverse drug categories are: anti-microbial agents, cardiovascular drugs, nervous system drugs, biological and biochemical products, diuretics, intravenous drugs, anti-inflammatory drugs, anti-cancer drugs, antipyretic and analgesic medicine. The high incidence of adverse drug reactions, in addition to the chemical structure of drug-related or drug formulations, but also to the extensive clinical use.

Old higher rate of adverse drug reactions - adverse reaction - the pharmaceutical industry sectors

By: xiao5096r

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