People With Depression May Fare Worse On Medication

Published in Archives of General Psychiatry, a recent research presents proof that

one-fifth of people with depression may get worse if put on a medication. "Based on combined data from previous studies, these assertive conclusions raise concerns about the efficacy of antidepressants if patients do not report a rapid improvement of depression symptoms, shares lead study author Ralitza Geuorguieva from the Yale University School of Health.

You know within the first couple weeks whos the most likely to benefit because theyre already starting to show improvement. I think this finding holds true for the antidepressants that are most commonly used today, according to a psychiatrist from the University of Pennsylvania Perelman School of Medicine, Dr. Michael Thase, who was not engaged in the research.

The American College of Obstetricians and Gynecologists recommended that pregnant women and also women planning to get pregnant should keep away from using antidepressants like Zoloft and Paxil. A 2010 research of the Swedish Medical Birth Register (MBR) backed up this recommendation with the results of their study.

Antidepressant drugs, such as Zoloft, bring severe side effects to women who were prescribed with this drug during the first three months of pregnancy, as was reported by the US Food and Drug Administration (FDA). Newborns may suffer from congenital birth defects and withdrawal symptoms that could last for months and even years. The infants heart deformities generally occurred when the mother was taking Zoloft during the first trimester of pregnancy, during which the babys heart was still in the process of development in the womb.

Another serious Zoloft side effect is pulmonary hypertension of the newborn (PPHN), which is a subtle form of high blood pressure in the lungs of the baby. Other defects are limb abnormalities and craniosynostosis, which refer to the deformation of the skull. It was also known that newborns may also have low blood sugar and experience difficulty in breathing, vomiting, seizures, tremor and irritability.

Medical specialists said that it is important to properly verify the type and timing of the medications prescribed for pregnant women, as well as those who are planning to get pregnant soon. Therefore, the public specifically the women should always consult a doctor before taking any medicines to avoid any unfortunate repercussions.

The public should also be informed about the numerous Zoloft lawsuit being filed presently by affected patients against Pfizer, the drug manufacturer. Pfizer knew of the dangerous birth defects associated with Zoloft use during pregnancy from the preclinical studies and the subsequent published studies confirming these risks. Pfizer took no action to properly study Zoloft or did not properly publish the results of the studies it did do, which would have reflected that risk, a lawsuit filed by a Missouri couple claims.

by: Angelena E. Mays

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