Predisposing Factor for AD

Author: bcured

Author: bcured

Alzheimers disease (AD) was not the rare condition Alzheimer believed it to be, but rather, was the most common cause of senile dementia. Early-onset AD usually has a genetic element, whereby it is inherited in an autosomal dominant fashion. Genetic linkage analyses have led to the identification of four genes associated with a subset of cases of early-onset AD. An estimated 90% of AD cases are classified as being late-onset. Around 95% of the late-onset AD cases are sporadic in nature, lacking alterations in the known set of genetic markers, which suggests either environmental causes or a combination of environmental and predisposing genetic determinants. A considerable number of studies have been completed over the past 20 years to assess whether or not the presence of HSV-1 in the aged brain is associated with AD using increasingly more sensitive techniques. Although there are some contradictory findings, by and large, the studies indicate that HSV-1 is found commonly in the brains of individuals who had AD. With the advent of more sensitive polymerase chain reaction (PCR) techniques, the consistent detection of HSV-1 has indicated a strong correlation between HSV-1 in the brain and AD. The more recent PCR-based studies also indicated that HSV-1 is found at fairly high frequency in normal aged human brain, but is absent from most younger human brain samples examined. An absence of central nervous system (CNS) infection by a member of the herpes virus family was established, supporting the association of HSV-1 with AD. HSV-1, on its own, is not the sole causative agent because AD develops in a subset of those individuals with evidence of CNS infection but it is an established risk factor for AD. Similar to the association of HSV-1 and AD development, high frequency of recurrent HSV-1 disease is seen only in a subpopulation of HSV-1-infected humans. Most individuals are infected with HSV-1 early in life and this often results in only mild and self-limited or inapparent disease. Local replication seeds in innervating sensory nerve endings, which provides access to the peripheral nervous system (PNS), where HSV-1 establishes a life-long latent infection in sensory neurons, thereby escaping the host immune response and creating a reservoir for viral production. Reactivation leads to asymptomatic shedding or recurrent disease and the potential for the establishment of a latent infection in the CNS. It has been theorized that frequent HSV-1 reactivation in the CNS may lead to increased injury and neuronal loss and that this may predispose individuals to the development of AD. Cure of herpes then becomes a necessity. Herpes cures are among the most difficult dermatological treatments to have success with. Sure, there are antiviral drugs available, which can help, but they take time to process through the digestive tract to have a full systemic effect on herpes. As new chemical drug options are not viable, alternative antiviral herpes cures are being investigated with great interest. Recent scientific studies of medicinal antiviral plant extracts show very encouraging results for a herpes cure, and have sparked a new methodology for treating herpes. Studies of these antiviral extracts demonstrate that many of these compounds exhibit significant anti-herpetic activity. Several actually inactivate HSV with great effectiveness. These antiviral extracts represent new effective treatment options for therapeutic use as virucidal agents for recurring herpes infections. HSVCurative is a potent all natural antiviral cure for herpes, highly effective against HSV1 and HSV2, it has a wide spectrum of antiviral activity against these viruses, even for genital herpes. The cure in this treatment has the ability to inactivate and destroy HSV, which has been established in published clinical trials. It is to be applied directly to an outbreak. HSVCurative is used specifically to treat HSV1 and HSV2 infections and acts as a curative agent against both these strains of herpes. It exhibits a pronounced anti-herpetic activity against HSV1 and HSV2 and, unlike other cures for herpes, actually kills these viruses upon exposure regardless of location on the body. The herpes cure applied to lesions or open sores is quickly absorbed into the circulatory system in significant quantities; hence use of organic material is absolutely essential in herpes cures. The importance of applying certified organic material to outbreaks or open sores cannot be overstated. To learn more, please go to http://www.bcured.net.About the Author:

staff of Nature Power Company, which is a network company dedicated to promoting customers' websites and developing softwares. You can go to the following websites to learn more about our natural organic products. http://www.bcured.net http://www.naturespharma.org

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