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Softgel Capsule Benefits In Natural Health And Pharmaceutical Products

Soft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling

absorption and enhancing bioavailability of both insoluble and lipid-soluble compounds. In addition, soft gels offer many other key advantages and therapeutic benefits:

Ease of Swallowing

Convenience

Acceptability


Dosage Accuracy

Uniformity and precision dosage

Adaptability

Liquid

Semi-solids

Suspension

Emulsion

Product Security

Dosage and formulation are tamper-resistant (a punctured or tampered softgels will leak or become discoloured)

Protection against counterfeit

Product Stability

Sealed container

Protection from light for photosensitive formulations

Masking of objectionable odors and tastes

Protects drug from oxidation and degradation

Market Differentiation

Size, shape and colour customization

Imprintability of capsules

Softgel technology

Softgel benefits of Biological and marketing advantage:

Better protection of active ingredientshermetically sealed dosage form protects drug from oxidation and degradation.

Improved absorption and bioavailability any formulations in softgel can enhance bioavailability or produce a quicker onset of action.

Marketplace differentiationa nearly endless array of shapes, sizes and shell colors helps your product stand out from branded or generic competitors.

Consumer preferenceresults of studies done through the years show that consumers expressed their preference for softgels in terms of ease of swallowing, perceived speed of delivery, lack of unpleasant odor or taste, and modern appearance.

Tamper evidencea punctured or otherwise tampered softgel will leak or become discolored, indicating a potential problem.

Formulation characteristics:

Self-emulsifying/microemulsion vehicle systems

Liquid (solution or suspension) fills

Wide range of softgel-compatible vehicles (hydrophilic/lipophilic)

Virtually unlimited selection of shapes, sizes and colors

Unique formulations leading to patentable line extensions

New technologies, including innovative shell forms and manufacturing techniques

Key advantages:

Enhanced bioavailability

Minimizes patient-to-patient variability

Possible lowered drug dosing

Excellent dose uniformity

Obvious evidence of tampering

Ability to solubilize a wide range of active ingredients

Maximizes drug loading

Extensive product differentiation possibilities

Enhanced life-cycle management

By Nutralab Canada Ltd. ( www.nutralab.ca)

by: David Backham
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