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Spina Bifida - One Of The Birth Defects With A Nice Name, But An Ugly Meaning

With all the great advantages that Lexapro as an SSRI (selective serotonin reuptake

inhibitor) class antidepressant has, with all the safety and efficacy it has proved, it still is a medication, it still has possible side effects and it can still be risky to use. This is especially true for pregnant women, who by the nature of their condition are exponentially exposed to risk factors. Lexapro in their case is a potential source of dangers lurking in depression treatment, due to increased chances of developing one or another of the Lexapro birth defects.

Spina bifida, the Latin for split spine, is a developmental congenital disorder in which the embryonic neural tube fails to close completely, resulting in one or more (not fully formed) vertebras remained unfused and open. Through a large enough opening, a portion of the spinal cord may protrude in the bones. In some of the cases a fluid-filled sac surrounds the spinal cord. There are four categories of spina bifida, the most significant of them being myelomeningocele, a condition that leads to disability in most of those affected.

Studies that discuss the link between SSRI intake and a Lexapro birth defect point out the increased incidence of myelomeningocele in children exposed to the drug during the pregnancy of their mothers. It is a cause for reflection and careful weighing of available options for women who plan on having a baby.

The neural tube opening can be closed by surgery, but unfortunately there are no chances to restore the normal function to the affected segment of the spinal cord. As a thing of the future, a new procedure, where intrauterine surgery is performed is currently being investigated for efficacy and safety. While this is giving hope to future mothers, for those already affected by spina bifida or other birth defects Lexapro use might result in, the pain is there to stay.


Paralysis does not always occur in the affected children, but the chances for its development are alarmingly high. Some of the children might be able to walk unaided, some will probably need short leg braces, but there will be others, who will only be able to maximize their movement with the use of a wheelchair. One thing is for sure: children affected by Lexapro and births defects linked to it, especially the like of spina bifida that have no cure yet, often live a life of constant affliction. The necessary periodical visits paid to orthopedists, neurosurgeons, or urologists are not only time-consuming, but they also demand a considerable financial effort from the entire family.


The actual cause of spina bifida is not yet known, but just like many other Lexapro birth defects, this congenital disorder is likely to develop during early pregnancy, often when the mother is not even aware of being pregnant.

Knowing this, it is easy to see why it is wise for a future mother to prepare in time for childbearing. A review of lifestyle, eating habits and emotional stress management will accentuate the changes that are to be made before conception. As a small example, it is known that the incidence of spina bifida can be decreased to as much as 70% if daily supplements of folic acid are taken prior to conception.

Act responsibly and when you are prescribed Lexapro for your depression, inform your physician about an incidental plan of becoming pregnant, as that piece of information might change the entire treatment plan. Even if it is still a mystery how does Lexapro cause birth defects, the fact that it does, remains a fact and the best you can do is to take precautions. The next best step, when already faced with Lexapro birth defects, is to take legal action and obtain the damage compensation from the drug manufacturer. You may need to file a Lexapro birth defect lawsuit.

by: Caleb Chao'
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