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The Importance of T4 DNA Polymerase in Testing

The Importance of T4 DNA Polymerase in Testing


In DNA testing there are many factors that are looked at in order to provide reliable, conclusive results. One of those factors is a DNA polymerase. This is a specific type of enzyme that works as a catalyst to polymerize deoxyribonucleotides to form a single strand of DNA. One type of enzyme in particular is known as the t4 DNA polymerase.

These substances are perhaps most well known for the role they place in the replication of DNA. In fact, it is possible for the polymerase to read a strand of DNA as a type of template. It can then be used in order to synthesize a completely new strand. The new strand which has been polymerized is completely complimentary to the template as well as identical to the original. Magnesium is commonly used as an ion to begin the catalyst process.

At the current time, there is no type of polymerase that is known to be able to start a completely new strand. A nucleotide may be added onto a preexisting group, but this means that a primer is necessary in order for the first nucleotide to be added onto.


Choosing the right testing solution for your DNA testing needs relies upon selecting a company that is well versed in every area associated with the production of DNA, including full understanding of the t4 polymerase. This is the only way to be certain that you have chosen a company that will provide you with completely reliable results. Due to the fact that DNA testing can and is often used in a variety of different crucial arenas, including paternity testing and forensics, it is even more important to ensure that the choice for testing is of the utmost quality and reliability.

Making even one small mistake during the testing process could lead to results which are disastrous and which could potentially result in a number of unwanted circumstances, including the inability to resolve a crime. The selection of a testing authority should involve a full investigation of the company's credentials, the experience of key officials and a good understanding of the company's reputation in regards to reliable results.
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