There are quite a few different options when traveling to Iowa for a guided deer hunt, depending on whether you plan on driving or flying.
First off, you will need to coordinate with your Iowa hunting outfitter to determine if they provide pickup from local airports or if you are responsible for driving to the hunting location. Most providers will offer some type of pickup service, usually for a minimal extra charge. You also need to consider what you would like to do during your off time not hunting. If you plan on doing any site seeing or would prefer some extra flexibility for the guided deer hunt, it may be worth renting a vehicle for the week. If you do end up renting a vehicle, I would recommend getting a SUV. As I am sure you are aware the weather can be pretty nasty during deer hunting season. Many times you will be traveling in remote locations with possible high accumlation of snow. It is worth paying the extra fee to have a SUV versus a car when you are traveling in the midwest.
If you are planning on flying into Iowa for your guided deer hunt there are a few different options. Des Moines, Iowa's largest city, is centrally located and a good access point for flights. If you are planning on hunting in Western Iowa you can also consider flying into Omaha Nebraska which is located on the Nebraska/Iowa border. If your deer hunting outfitter is located in Northeast Iowa you can also consider LaCrosse Winconsin, which is very close to the Wisconisin/Iowa border. With these many options you won't be left with an extremely long drive in the middle of an Iowa winter!
Whichever method of transport you choose just make sure you plan accordingly. With the unpredictable weather it may be a good idea to allow yourself and extra travel day to ensure you are at your local outfitter the first day of the hunting season! Good luck with your Iowa Guided Hunt!