Mesothelioma is a kind of cancer that's almost always caused by exposure to asbestos. In this illness, malicious cells develop in the mesothelium, a protective lining that covers almost all of the body's internal organs. Its commonest site is the pleura ( outer liner of the lungs and internal chest wall ), but it may also happen in the peritoneum ( the lining of the intestinal cavity ), the heart, the pericardium ( a sac that surrounds the heart...more
If a case seems to be going well for the plaintiff the defendant might offer a settlement. If this happens the plaintiff's attorney might recommend that either they negotiate for a higher amount or that the defendant should refuse the offer in anticipation of a large award should they win the case.Out-of-Court Malignant Mesothelioma Settlements By: Wendy Moyer About the Author Next, if you or a loved one suffers from an...more
Trying to better understand the mechanism of mesothelioma disease has been the goal of many researchers. Some believe that a threshold may exist between duration and intensity of asbestos exposure and the induction of mesothelioma. One interesting study is called, Possible role of lipid peroxidation in the induction of NF-kappa B and AP-1 in RFL-6 cells by crocidolite asbestos: evidence following protection by vitamin E. by S P Faux and P J Howden - Environ Health Perspect. 1997 September; 105(Suppl 5): 11271130. Here is an excerpt: Abstract - Asbestos fibers cause persistent induction of the oxidative stress sensitive transcription factors nuclear factor kappa-B (NF-kappa B) and activator protein-1 (AP-1) in mammalian cells. These transcription factors play an important role in the regulation of cellular activity. Lipid peroxidation, mediated by reactive oxygen species, is thought to be a possible mechanism in the pathogenicity of asbestos fibers. These studies were designed to determine if crocidolite asbestos-induced lipid peroxidation plays a role in the mechanism of formation of NF-kappa B and AP-1. Treatment of a rat lung fibroblast cell line (RFL-6) with crocidolite...more
Occupational exposure to asbestos causes the death of thousands of people each year. This has led to an almost unparalleled body of research trying to better understand asbestos and its link to mesothelioma disease. One interesting study is called, Kinetics of the bronchoalveolar leucocyte response in rats during exposure to equal airborne mass...more
When asbestos fibers are broken into small pieces they can be swallowed or inhaled and lead to mesothelioma disease. This disease is responsible for the deaths of thousands of people each year, and consequently is the subject of a great deal of research. One important study is called, Secreted extracellular domains of macrophage scavenger...more
When asbestos fibers are inhaled, they can attack the membranes surrounding the heart, lungs and abdomen and lead to disease development. Mesothelioma alone causes the death of over 2,000 people each year. Identifying the links between this deadly disease and asbestos exposure are important and ongoing. One important study is called, The epidermiologic relationship between pleural mesothelioma and asbestos exposure. by Nurminen M. - Scand J Work Environ Health. 1975 Jun;1(2):128-37. Here is an excerpt: Abstract - This paper describes an investigation of 85 notifications of either probable or possible mesothelioma to the Finnish Cancer Registry from 1953 through 1969. The investigation covers characteristic epidemiologic features and the possibility of the mesothelioma being connected with occupational or other exposure to asbestos. The incidence rate of pleural mesothelioma was estimated at 1.1 per million per year. The male/female ratio was 1.3:1, which greatly differed fsrom that for malignant neoplasms of the bronchus or lung in Finland in 1960. The mean age at death from mesothelioma was over 7 years lower than that for bronchial carcinoma. The ratio of the crude incidence...more
Manual laborers suffer from mesothelioma disease in an inordinate amount. This has been the subject of much research. One important study is called, Analysis of the cores of asbestos bodies from members of the general population: patients with...more
The development of mesothelioma disease has been linked to asbestos exposure. One interesting study examining this relationship is called, The Hygiene Standard for Chrysotile Asbestos - The Lancet, Volume 311, Issue 8062, Pages 484-489. Here is an...more
Under the Safety, Health and Welfare at Work (Construction) Regulations 2006, there is the specific requirement to identify any particular risk including the possibility of the presence of asbestos-containing materials in a building and asbestos or...more
There have been numerous allegations that in the past corporate officers knew about the potentially lethal effects of asbestos and that they deliberately decided to withhold that knowledge in order to bolster their company's bottom lines. After...more
Asbestos cancer mesothelioma is a disease that is caused by exposure to asbestos for an extended duration of time. Asbestos was at one time deemed to be a magic material owing to its qualities such as being light weight, resistance to heat, etc. It...more
A cure for malignant mesothelioma does not yet exist, but people with the disease may still choose to undergo a mixture of treatment methods for their malignancy or additionally take part in clinical trials. The malignant mesothelioma treatment...more