subject: Nitric Oxide Analyzer [print this page] The aim of this work, a short ARDS patients, their families and nitric oxide gas, and clinical consequences of the characteristics associated with the use of family members present. Nitric oxide (NO), it is not nitrous oxide (N20) is mixed, a light anesthetic is often used by dental professionals is known as "laughing gas, is". In fact, nitric oxide is a pollutant known as the general environmental contaminants during the production of nitric oxide. However, in general, sulfur dioxide and nitric acid to the reaction. Nitric oxide, a component of smog, urban air, 10,100 per million (ppb can be measured in part), of course, the upper and lower respiratory 100-100 ppb occur in the body is now burned in 1000 was 400 ppm (p. / min). Clinical studies have found that the concentration of exhaled NO increases during exercise, and patients with asthma.
Inhaled NO is relatively new administration, U. the S. Food and drug abuse (FDA) and pharmaceutical research to clinical trials, many of the buildings are used for this gas. Approved by the FDA until the device is used in the evaluation and undergo drug testing and the process of applying for a license (known Asan New Drug [IND number] Studio) to carry out such studies been limited by NO. In addition, the process of informed consent, each patient or legal representative must be obtained for the administration of NO.
Physiology of ARDS
Those who know this newsletter for more information on ARDS may have several doctors and researchers. However, a limited study of pulmonary ARDS, it is necessary, so not to cause lung disease.
Patients with ARDS, or stomach contents (the desire to change precipitated a source of inspiration), injuries, pneumonia, toxic substances, and somewhere in the body of a serious infection (Sepsis in inhalation) have high blood pressure and blood-free About lungs (pulmonary hypertension) .. In addition, in normal conditions, the small air the lungs (alveoli) in the air bubble does not do enough, or leave it (twice), head of the alveoli to be a blood (or get a smaller narrower). ARDS, however, automatically underventilated alveoli, or continue to receive the supply of blood vessels (capillaries from). because it is unconscious or alveoli underventilated not receiving oxygen, oxygen can not give blood. net effect may be severe depletion of oxygen in the blood.
General Sciences
Some substances that occur naturally in the body properly control the flow of blood around the lungs. This material-lung blood (greater than or expand into a wider vasodilatation) may cause. Vasodilation of blood cell production of products covered in this case the gas produced by NO. Do not explain the physiological effects vasodilators such as nitroglycerin, used to treat high blood pressure medicine a. Many studies have shown that overproduction not play low blood pressure and body mass vasodilation septic shock syndrome related to the paper.
Given the form of gas that can be applied to pulmonary gas inhalation administration as scheduled. What this means is that when inhaled, just select the lungs dilates blood vessels, and an active exchange of gases (oxygen and carbon dioxide) and alveolar-capillary participated in these parts. In other words, the areas of the lungs and blood, is the flow of oxygen and, therefore, to improve the level of oxygen in the body. This is a ventilation-perfusion (V / Q) is known as the next.
