subject: 2010 New England Patriots: NFL Schedule and Odds [print this page] New England will host the Indianapolis Colts on November 21st in a match-up of the two most dominant teams in NFL odds for well over a decade. That is followed with a Thanksgiving Day game vs the Detroit Lions on November 25th. On December 6th the Pats host the Jets in what could be an AFC East Division title match for Monday Night Football. The final quarter of the Patriots 2010 NFL schedule starts with two tough games beginning at the Chicago Bears on December 12th and then at home against the Green Bay Packers on December 19th. The Pats will wrap up the schedule with division games at Buffalo the day after Christmas and then at home against Miami on January 2nd.