subject: Arthritis Cream: Does It Work? [print this page] Capsaicin is the active ingredient in chilli peppers. When used as an arthritis cream, capsaicin can be applied to sore muscles and joints to relieve inflammation and pain. Capsaicin relieves pain in two ways: It can interfere with the enzymes causing the inflammation in the joint, and it can interfere with the pain impulses sent to the nervous system. The relief you feel is only temporary, so it needs to be applied at least twice a day. If this means you can get by with fewer painkillers (NSAIDs), you have won a small battle against your arthritis. Capasiacin can also be taken orally as an effective way to relieve migraines, headaches and cluster headaches because of acting in on the nerve pathways. Some preliminary tests also show that it inhibits the growth of prostrate cells in petri dishes and slowed the growth of tumors in mice. It is also know to relieve sinus pain and relieves congestion. Furthermore, cultures eating a lot of chillies have a lower occurrence of heart disease. This is because capsaicin reduces cholesterol and triglyceride levels.