subject: Use of omega 3 fatty acids [print this page] Mechanisms of action of omega-3 PUFAs in other parts of the hemostatic system (in particular, found a decrease of fibrinogen, activation of the fibrinolysis system) are not fully understood. Hypolipidemic action of fish oil is to suppress the synthesis of lipoproteins of very low and low density, improve their clearance and increasing the excretion of bile. Lately we hear a lot of unflattering words to arachidonic acid (AA). Apparently, you need to cite several arguments in defense of this matter.
In terms of health, when excessive vasoconstriction and bronchoconstriction are not provided, there is no need in excess of vasodilators and bronchodilators.
It should be noted that the release of AA from the cell membrane and subsequent metabolism occurs in response to a variety of factors (stress, hypoxia, catecholamines, collagen, antigen-antibody reaction, etc.). So, in terms of disease under a variety of pathological conditions is a nonspecific compensatory-adaptive reaction is transformed into the pathological. Hyperproduction of constrictor factors, activators trombagregatsii already acquired the clinical significance and requires correction.
Thus, in conditions of disease to humans are more beneficial metabolites EPA, since among them is dominated by chemicals that are inflammatory and inhibit platelet aggregation properties.
If the diet of a healthy person to completely eliminate the AK, it will only bring negative results, since the metabolites of EPA are not fully implemented those functions that perform metabolites of AA. Confirmed by the results of epidemiological studies: the inhabitants of coastal areas, are exclusively products of the sea, do not suffer from atherosclerosis, but they have increased bleeding, frequent development of hemarthrosis in response to the slightest injury, hypotension.
With regard to the sick person, only small change in diet would be something difficult to fix. That's why they need appropriate concentrates or drugs.
