subject: Drug Guide: Special Populations Need To Be Used With Caution Taking Antipsychotic Drugs - Side [print this page] Current clinical use of antipsychotic drugs are about 20 species of the chemical subject to benzodiazepine class, is 60 years since the last century, the most commonly used since a large class of sedative hypnotic drugs, drugs of many families standing. The main effect of these drugs inhibit the central nervous system, resulting in sedative, hypnotic, anxiolytic, anticonvulsant, antiepileptic, and relaxation of muscles. Although these drugs is effective, side effects are relatively small, but there is addiction, by the National Ministry of Health as a Type II management of psychotropic drugs. Some insomnia Scared of such drugs, many of the emergency room several times because of unreasonable taking these drugs save lead to poisoning of the patient, who therefore do need to take note of the following four areas:
One choice taken by insomnia The role of antipsychotic drugs in accordance with the length of time is divided into short-acting, in effect, long-acting categories. Insomnia, sleep difficulties are advised to take short-acting of oxazepam, triazolam, early awakening insomnia are advised to take the effect of diazepam, estazolam, alprazolam, insomnia, anxiety disorders were associated with daytime should take such long-lasting flurazepam.
Antipsychotic drugs should be taken in accordance with the role of the strength of selection. Early symptoms of taking an option to choose a lesser of diazepam, nitrazepam, severe symptoms before taking the role of the former 4-10 times stronger than the triazolam, estazolam, alprazolam, etc..
Second, strict control of dosage, note taking method
Small doses of this drug should be used on, must not overdose. Large doses lead poisoning can cause tremors, respiratory depression, hypotension, cardiac arrest or even slow, the end result of respiratory, circulatory failure and death.
Taking these drugs generally do not produce short-term dependence, patients with occasional insomnia can be chewed with the sublingual tablets, usually fall asleep after half an hour. But even serving more than two weeks or more easy to produce dependence, be gradually discontinued, there will be a sudden withdrawal insomnia, anxiety, agitation, tremor, and even convulsions and other withdrawal symptoms.
3, special caution and disabled people
Pregnant women these drugs can cause congenital heart disease, breast-feeding infants of women taking the body temperature can affect the regulatory function, and to extend the period of neonatal physiologic jaundice, it must be disabled.
Elderly patients had poor tolerance of these drugs, prone to lethargy, headache, fatigue, confusion, ataxia embolism, the dose should be taken as half of adults.
Emphysema patients taking may aggravate respiratory failure, glaucoma, myasthenia gravis, neutropenia can take sicker patients, with caution.
Can cause some patients due to hypotension, muscle weakness, blurred vision, mental disorders, so the driver to operate sophisticated equipment and high-altitude operations used with caution.
Because by liver and excreted through the kidneys, the liver and kidney dysfunction can lead to accumulation of poisoning, should be used with caution.
4, the interaction between drugs alert
These drugs and the sedative phenobarbital, chlordiazepoxide, and antiallergic aminophenyl maleate, cyproheptadine combined, can increase central inhibition and respiratory depression, to reduce the dose; and Easy addictive drugs such as analgesics pethidine, codeine antitussive combination, can accelerate the risk of addiction, to avoid combination; with antihypertensive drugs, cardiac drugs, diuretics, anti-Parkinson's disease drug combination, can be enhance the role of the latter, the need to reduce dose; with cimetidine, propranolol, isoniazid combination, increase the role of the former, the need to reduce dose; and rifampin combination, can reduce the latter effect, to increase dose; with combined contraceptives may accelerate the metabolism of contraceptive drugs, leading to contraceptive failure, should not be combined; and alcohol same service, may enhance the central nervous system inhibition, and even lead to coma or poisoning patients, not with the service.
