subject: Shanghai Scientists Have Cloned Sheep Subspecies Technology Through The Identification [print this page] Shanghai Transgenic Research Center for research in cloning sheep has access to new breakthrough technology, scientists have cloned by somatic cell methods, from the Boer goat ears nuclear extract from Saanen goats on behalf of the Aberdeen Maternity, the world's first six from the Asia interspecific somatic cell cloned Boer goat, grow 500 days after the adoption of technical appraisal.
Shanghai Transgenic Research Center Director Cheng Guoxiang told reporters that six survived the first Boer goat is the international way through the sub-species cloning cloning out, "The key is to be cloned Boer goat to get rid of body cell transplantation genetic material of Posa hybrid sheep oocytes in the middle. " Cheng Guoxiang introduced Boer goat is a globally recognized precious quality meat goats (each worth more than 10 thousand yuan), Saanen goats pregnant and breast feeding as the water enough, motherhood is good, can improve the survival rate of cloned sheep. As the two sheep that belong to different subspecies of "distant relatives", so they were cloned between the "sub-species."
Cheng Guoxiang, during the cloning experiment from last spring, researchers from a code SP3179, born only two months of the male goat's ears cut a large piece of fingernail, extraction of which play a key role for the family line the nucleus, in turn Boer goat and Saanen goats nucleus removed the egg nucleus, forming "eggs." The "eggs" SP3179 contains only the genetic material, through training and development to blastocysts and then implanted into six Saanen goats "surrogate mothers" go nurturing womb.
This six cloned sheep doll last year in April to August between the term natural childbirth. The most important were born 5.65 kg, the lightest of 2.3 kg. Than ordinary goat, this clone grows to slightly faster six brothers, and now each have four or five kilograms.
At the same time, Shanghai Transgenic Research Center, researchers transgenic and somatic cell cloning method, to make goat milk in the secreted human lysozyme and human lactoferrin. Related technologies currently patented, and some have been authorized. Scientists plan bred 2000 with 3 years of human lysozyme transgenic goats to produce 1.5 tons of high activity the ability of pure human lysozyme.
The nutrients in human milk is to enter the goat? According to Cheng Guoxiang introduction, researchers of human lactoferrin gene will be injected into a goat egg in order to cultivate with human lactoferrin transgenic sheep. Another stud sucked into the human lysozyme gene somatic cells in goat fetus, by way of cloning to breed the next generation of secretion of human lysozyme.
Cheng Guoxiang explained that lysozyme can antibacterial anti-drug and apply a variety of facial features and a variety of inflammatory skin diseases, but a lot of natural human lysozyme is difficult to obtain. According to the analysis of such goat milk showed that levels of human lysozyme in which more than 2.5 mg per ml, up to 4 mg per milliliter, much higher than the content of human milk lysozyme (0.4 mg per ml).
This batch of sheep genes have a professional nurse name: mammary gland bioreactor, which can liken them to "animal pharmaceutical companies."
