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subject: Microscopy Markets -new Medical Report Of Aarkstore Enterprise [print this page]


This Publications report deals primarily with the analysis of market segments of microscopes used in clinical and research laboratories. Emphasis is on the U.S. markets; however, the worldwide markets are analyzed and discussed as well. Specifically, this report examines those companies and products which are actively developing and marketing microscopy devices and supplies in market segments which have the potential for growth rates above 5% per year over the next five years. It continues to examine those microscopy devices operated as light, confocal, electron and scanning probe microscopes. Also analyzed are applications for certain microscope technology platforms such as semi-conductor processing systems and automated imaging systems. Concentration is centered on an overview of individual microscopy markets, which are believed to possess the elements that will lead to sustained growth rates for the foreseeable future. This report assesses the current status of each market, makes projections for market size, discusses the market strategies of leading companies in each market segment, and evaluates the forces that underlie the high growth of each segment. Additionally, theres an overview of the instruments and supplies marketed by major companies in each market segment. Analysis of the market size, growth rates, and market components for instruments used for microscopy are also discussed.

Table of Contents :

1 Overview 6

1.1 Statement of Report 6

1.2 Scope of This Report 6

1.3 Objectives 7

1.4 Methodology 8

1.5 Aims of This Report 9

1.6 Executive Summary 9

1.7 Trends and Conclusions 10

2 Introduction to Microscopy Markets 11

2.1 Overview of Microscopy Technologies 11

2.1.1 Introduction 11

2.1.2 Basic Optical Microscopy (OM) 11

2.1.3 Electron Microscopy (EM) and Other Charged-Particle Technologies 12

2.1.4 Advanced Optical Microscopy 13

2.1.5 Scanning Probe Microscopy (SPM) 13

2.1.6 Fourier Transform Infrared Microscopy (FT-IR) 14

2.1.7 Ultraviolet Microscopy (UVM) 14

2.1.8 Scanning Acoustic Microscopy (SAM) 14

2.1.9 X-Ray Microscopy / Microtomography (MCT, XMT, Micro-CT) 14

2.2 Market Perspective 14

2.3 Market Analysis 15

2.3.1 Market Size 16

2.3.2 Market Share 17

2.3.3 Key Players 17

2.3.4 Competition 18

2.3.5 Barriers to Growth 18

2.3.6 Market Drivers 18

2.4 Purchasers Perspectives 19

3 In-Depth Discussion of Optical (Light) Microscopy (OM) 21

3.1 Lens Systems 22

3.2 Resolution 23

3.3 Illumination Systems 23

3.4 Innovations 24

3.4.1 Stereo Microscopes 24

3.5 Major Applications of Optical Microscopy 25

3.5.1 Semiconductor Manufacturing 25

3.5.2 Automated Medical Imaging 26

3.5.3 Market Drivers for Automated Systems for Semiconductor and Medical Applications 28

3.5.4 Real-Time Imaging 28

4 In-Depth Discussion of Light-Based Fluorescence, Multi-Photon and Confocal Microscopy 29

4.1 Fluorescence Microscopy 29

4.2 Total Internal Reflection Fluorescence Microscopy (TIRFM) 30

4.3 Multi-Photon Microscopy 30

4.3.1 Basic Principles 30

4.3.2 Lasers 30

4.3.3 Fluorophores for Multi-Photon Work 31

4.3.4 Uncaging 31

4.3.5 Autofluorescence 31

4.4 Laser Scanning Confocal Microscopy (Confocal, LSCM) 31

4.4.1 Basic Principles 32

4.4.2 Confocal System Types 33

4.4.3 Photobleaching 33

4.5 High-Throughput Fluorescence and Confocal Imaging Systems 33

4.6 Major Players and Products in Optical, Fluorescence, Multi-Photon and Confocal Microscopy 34

4.6.1 BD (Becton, Dickinson and Company) 34

4.6.2 KLA-Tencor Corporation 34

4.6.3 Korima, Inc. 35

4.6.4 Leica Microsystems, Inc. 35

4.6.5 Nikon Instruments, Inc. 38

4.6.6 Nanomics Imaging, Inc. 39

4.6.7 Olympus Imaging America, Inc. 39

4.6.8 Veeco Instruments, Inc. 40

4.6.9 Carl Zeiss Microimaging, Inc. 41

4.6.10 Modular Confocal Scanners 42

5 In-Depth Discussion of Scanning Probe Microscopy (SPM), Including Near-Field (NSOM) and Atomic Force Microscopy (AFM) 44

5.1 Introduction 44

5.2 Near-Field Scanning Optical Microscopy (NSOM) 44

5.2.1 Resonance Frequency 45

5.2.2 Aperture 45

5.2.3 Reflection Mode 45

5.3 Near-Field Scanning Thermal Microscopy (NThM) 45

5.4 Atomic Force Microscopy (AFM) 45

5.4.1 Semiconductor Applications 46

5.4.2 Magnetic Material Applications 46

5.4.3 Electrochemical Applications 46

5.4.4 Life Sciences Applications 46

5.5 Major Players and Products in Scanning Probe Microscopy (Including Near-Field and Atomic Force) 47

5.5.1 Agilent Technologies 47

5.5.2 Asylum Research 47

5.5.3 JEOL USA, Inc. 47

5.5.4 KLA-Tencor Corporation 48

5.5.5 Nanonics Imaging, Ltd. 48

5.5.6 Omicron NanoTechnology GmbH 49

5.5.7 Veeco Instruments, Inc. 49

5.5.8 WITec Instruments Corp. 51

6 In-Depth Discussion of Infrared and Ultraviolet Microscopy 52

6.1 Fourier-Transfer Infrared Microscopy (FT-IR) 52

6.2 Ultraviolet Microscopy (UVM) 52

6.3 Major Players and Products for Infrared and Ultraviolet Microscopy 53

6.3.1 Bruker Optics, Inc. 53

6.3.2 Craic Technologies 53

6.3.3 KLA-Tencor Corporation 53

6.3.4 Korima, Inc. 54

6.3.5 Thermo Scientific 54

7 In-Depth Discussion of Scanning Acoustic Microscopy, X-Ray Microtomography and Raman Spectroscopic Microscopy 55

7.1 Scanning Acoustic Microscopy (SAM) 55

7.2 X-Ray Microtomography (CTM, Micro-CT) 56

7.3 Raman Spectroscopic Microscopy 56

8 Major Players and Products in Acoustic Microscopy, X-Ray Microtomography and Raman Microscopy 58

8.1 Major Players in Acoustic Microscopy 58

8.1.1 Sonix, Inc. 58

8.1.2 Sonoscan, Inc. 58

8.2 Major Players in X-Ray Microtomography 59

8.2.1 Cameca Instruments, Inc. 59

8.2.2 SkyScan 59

8.3 Major Players in Raman Microscopy 59

8.3.1 Horiba Jobin Yvon, Inc. 59

8.3.2 Renishaw, Inc. 60

8.3.3 Thermo Scientific 60

9 In-Depth Discussion of Electron Microscopy (EM) and Related Charged-Particle Systems 61

9.1 Transmission Electron Microscope (TEM) 61

9.1.1 Electron Sources 62

9.2 Scanning Electron Microscope (SEM) 63

9.2.1 Rastering 63

9.2.2 Exploring the Sample 64

9.2.3 Types of Image 64

9.2.4 Environmental SEM (ESEM) and Variable-Pressure SEM (VPSEM) 65

9.2.5 Low-Voltage SEM 66

9.2.6 Tabletop Models 66

9.2.7 Applications 66

9.3 Scanning/Transmission Electron Microscope (STEM) 66

9.4 Electron Probe Microanalyzer (EPMA, Microprobe) 67

9.5 Auger Electron Microscopy/Spectroscopy (AES, AEM, Auger) 68

9.6 Electron Beam (E-Beam) Lithography 68

9.7 Focused Ion Beam (FIB) and Dual-Beam Microscopes 69

9.8 Secondary Ion Mass Spectrometry (SIMS) 69

9.9 X-Ray Photoelectron Spectroscopy (XPS)/ Electron Spectroscopy for Chemical Analysis (ESCA) 70

9.10 Scanning Helium Ion Beam Microscopy (SHIM) 70

10 Ancillary Analytical Attachments 71

10.1 Common/Historical Attachments 71

10.1.1 Energy-Dispersive (EDS) and Wavelength-Dispersive (WDS) X-ray Microanalyzers 71

10.1.2 Electron Backscatter Diffraction (EBSD) 71

10.1.3 Cathodoluminescence (CL) 71

10.1.4 X-Ray Microtomography 71

10.1.5 Raman Spectroscopy 72

11 Major Players and Products in Electron Beam and Other Charged-Particle Beam Microscopies 73

11.1 Cameca Instruments, Inc. 73

11.2 FEI Company 74

11.3 Hitachi High Technologies America, Inc. 79

11.4 JEOL USA, Inc. 81

11.5 KLA-Tencor Corporation 86

11.6 Omicron NanoTechnology GmbH 86

11.7 Vistec Lithography, Inc. 87

11.8 Carl Zeiss SMT Corporation 88

12 Company Profiles 90

12.1 Applied Materials, Inc. 90

12.2 Applied Precision, Inc. 91

12.3 Becton, Dickinson and Company 91

12.4 Bio-Rad Laboratories, Incorporated 92

12.5 Bruker Optics 93

12.6 Buehler 93

12.7 Cameca 94

12.8 Carl Zeiss, Inc. 94

12.9 Danish Micro Engineering A/S 96

12.10 FEI Company 97

12.11 Gatan 98

12.12 Genetix 99

12.13 Hitachi, Ltd. 99

12.14 Inami Corp. 101

12.15 IRIS International 101

12.16 JEOL 103

12.17 KLA-Tencor Corporation 104

12.18 Leica Microsystems (part of Danaher Corporation) 107

12.19 Medical Integrated Services (MIS) 108

12.20 Nanonics Imaging, Ltd. 108

12.21 Nikon, Inc. 109

12.22 NT-MDT 110

12.23 Obducat-CamScan 110

12.24 Olympus Corporation 111

12.25 Omicron Nanotechnology 113

12.26 Pacific Nanotechnology 113

12.27 Park Systems (formerly PSIA) 113

12.28 PerkinElmer 113

12.29 Quesant Instruments 119

12.30 Questar Corporation 119

12.31 Schott North America 120

12.32 Shimadzu Corporation 121

12.33 SII NanoTechnology 121

12.34 Thermo Fisher Scientific, Inc. 121

12.35 TM Microscopes (ThermoMicroscopes) 125

12.36 TriPath Imaging, Inc. 126

12.37 Veeco Instruments 126

12.38 WITec (Wissenschaftliche Instrumente und Technologie) GmbH 128

13 Company Directory 129

INDEX OF FIGURES

Figure 2.1: Global Market for Microscopes, Accessories and Supplies, 2003-2012 16

Figure 3.1: Basic Components of the Optical Microscope 21

Figure 3.2: Stereo Microscope 24

INDEX OF TABLES

Table 2.1: Global Market for Microscopes and Accessories, 2007-2013 16

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