subject: Xinjiang Four Kinds Of Effects On The Cardiovascular System Characteristics Herbal - Herbal Medicine [print this page] Xinjiang is vast, complex and geographically diverse environment and ecological conditions, gave birth to a rich and unique resources of medicinal plants. World Health Organization, cardiovascular disease has been identified as hazardous to human health, "the number one killer." From the medicinal plant resources in Xinjiang, to find effective treatment for cardiovascular diseases, special medicines, and to conduct its research, development and use, has great practical significance. Now the safflower, snow lotus, licorice and Rhodiola 4 characteristics of Xinjiang herbal effects on the cardiovascular system are reviewed.
1 lower blood pressure Safflower safflower for the Compositae CarthamustinctoriusL.'s Dried tubular flower, warm, spicy, with promoting blood circulation by, the effect of bulk deposition pain, with yellow Ketone , Safflower polysaccharides, organic acids, hydroxyl yellow A, yellow, red flowers, red pigment, riboflavin and other ingredients. Safflower yellow brown powder extracted from a variety of yellow in anesthetized dogs, rabbits have a significant antihypertensive effect. The mechanism is mainly direct expansion of peripheral vascular and coronary blood vessels, thus increasing the traffic flow, blood pressure decreased [a]. The clinical application of safflower yellow injection in the treatment of hypertension, coronary heart disease and achieved good results.
Compositae Saussurea involucrata Saussurea involucrata is SaussureainvolucrataKar.etKir the whole plant, with menstrual blood, causing problems impotence dehumidification and the effect of gluten, contain flavonoids, alkaloids, lactones, sterols, polysaccharides and volatile oil and other ingredients. Saussurea which flavonoids can reduce blood pressure in anesthetized rabbits and dogs, the antihypertensive effect could be partially blocked by propranolol [2]. Saussurea Tongmai pill for the treatment of coronary artery disease with good results.
2 lipid-lowering effect Is a leguminous plant Glycyrrhiza glabra Glycyrrhiza glabra GlycyrrhizaglabraL.'s Dried root and rhizome, nature, sweet, with detoxification, expectorant, analgesic, antispasmodic the effect, containing triterpenes, flavonoids, alkaloids and polysaccharide components. Which triterpenoids glycyrrhizin can reduce experimental atherosclerosis, serum Cholesterol (TC), prevent the development of atherosclerosis, light licorice flavonoids will be able to lipid [3]. Glycyrrhizin tablet can be used for the treatment of hyperlipidemia in patients after taking, TC, triglyceride (TG), low density lipoprotein cholesterol (LDL? C) were significantly decreased.
Plant Sedum Rhodiola Rhodiola is RhodiolaroseaL.'s All grass, with blood to stop bleeding, the effect of Qingfeizhike containing Rhodiola glycosides, aglycone tyrosol, flavonoids, organic acids, polysaccharides, coumarin, essential oil composition. Rhodiola has a role in prevention and treatment of hyperlipidemia, for mainly drug developed Nuodikang Rhodiola capsule can significantly improve lipid metabolism disorder hyperlipidemia symptoms [4]. Safflower seed oil is highly unsaturated fatty acids, linoleic acid content of up to 80% or more, can reduce blood fat and cholesterol and play a role in health care. The main role of linoleic acid to accelerate the conversion of cholesterol in the blood and excretion, have a good effect on lowering cholesterol [5]. Intake of safflower oil in the crowd, a very low incidence of cardiovascular diseases, American and European countries generally choose safflower seed oil as a cooking oil.
3 antioxidant Free radical oxidative damage can promote the development of coronary heart disease. Safflower can be effective against free radical oxidative damage, MDA levels in serum were significantly lower SOD activity was significantly higher [6]. Clinical use of safflower injection on coronary heart disease and achieved better results. Recent studies have found that Rhodiola Extract Superoxide radical and hydroxyl radical scavenging effects, indicating its antioxidant effect [7]. Canada's health care products have been developed Arctic Root Rhodiola Ginseng capsules, is Europe and the United States recognized the anti-aging nutritional supplements.
Glycyrrhiza glabra licorice in the light set, can inhibit the body's free radicals produced during metabolism, so sensitive to the oxidation of biological macromolecules (LDL? C, DNA) and cell wall such as oxidative damage from free radicals , can prevent the oxidation of free radicals related to some of the pathological changes, such as atherosclerosis, etc. [8]. Be present as a light licorice whitening agent applications, such as its lipid-lowering, antioxidant role of development, there will be a good prospect.
4 on vascular endothelium Safflower reduce shrinkage factor vascular endothelial cells release endothelin and thromboxane, increased endothelial cell release of relaxing factor nitric oxide (NO) and prostacyclin, play an expansion of blood vessels, improve microcirculation, platelet aggregation, relieve inflammatory mediators on vascular endothelial injury. Safflower injection can effectively prevent atherosclerosis, and can protect the target organs of hypertension. HSYA A concentration of 5.35 ~ 0.16mg / L, the human umbilical vein endothelial cells with inhibition, and with the lower concentration, the stronger its inhibition [9].
Rhodiola can inhibit rat heart and lung vascular endothelial cell proliferation and migration, protection of endothelium integrity and blood flow, thereby reducing pulmonary vascular resistance, increasing the oxygen content, can protect heart, the role of lung [10]. Tibetan Rhodiola capsules domain plateau for combating chronic heart disease, has a good effect.
5 on vascular smooth muscle Safflower with calcium antagonism can block the receptors on vascular smooth muscle cell membrane and voltage dependent calcium channel manipulation of calcium channels in calcium influx may be the mechanism of safflower one of the treatment of cardiovascular disease. In addition, yellow can inhibit the proliferation of vascular smooth muscle cells.
Salidroside can inhibit vascular smooth muscle cell proliferation under hypoxia and the hyperosmolar state of vascular smooth muscle cell contraction, can be used to control high altitude adaptation imperfecta [11]. Salidroside injection for the treatment of cardiovascular disease, results are obvious.
