Clean-in-Place is an automated technique. It is a reliable technique that provides efficient cleaning solutions for a number of safety equipments and other devices. It offers significant advantages to pharmaceutical manufacturing industries and other healthcare organizations. Processing equipment contains pumps, tanks, filters, valves, heat exchange units and other process piping. This cleaning method can effectively clean all these parts without disassembling. This also provides cost-effective and simple cleaning solutions.
Regular cleaning and proper maintenance of systems increases their efficiency, reliability, life span and reduces all sorts of cross-contamination of the machineries. This in turn maintains the quality of all the equipments. To achieve all these advantages, appropriate measurement and control of CIP method is required. Pharmaceutical manufacturing plants and other industries should have professionals to determine the exact amount of the cleaning solutions to be used. After cleaning is complete, the cleaning solutions should be properly removed from the devices before the next processing. Conductivity analysis should be used with Clean-in-Place technique for better results.
The main objectives of this technique are maximizing the safety of devices by avoiding all sorts of contamination and minimizing the cleaning time. This process includes a number of steps such as an initial and final drain, a pre-rinse, a sodium-hydroxide wash and finally a post-rinse. The time span of all these steps varies from each other. These steps are highly hygienic and reduce the level of bacterial contamination with the use of strong oxidants like hydrogen peroxide, ozone and other chlorine based compounds.
Hence we can say that this cleaning method is very effective and has given relief to a number of industries.
