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subject: Clomifen Citrate Is One Of The Most Famous Fertility Medications. [print this page]


This is because it is most frequently usedThis is because it is most frequently used. Almost 25% of female infertility issues involve a problem with ovulation. This medicine, being as a fertility drug, is easy to take since it comes in the form of pills not injections. The side effects are also fewer.

Clomifen Citrate is meant for making the recovery of natural testosterone production after steroid usage, and improving testosterone production of steroid users. It is also very effective in lessening risk of gynecomastia during a series using aromatizable steroids. Although it is claimed that this medicine stimulates the production of LH, and as a result testosterone, Clomifen Citrate actually works not by stimulation of the hypothalamus and pituitary, but by jamming their reserve of estrogen.

This drug is a mixed estrogen activator/blocker. When it is bound to the estrogen receptor, it puts it in a somewhat unusual conformation, unlike estradiol. The estrogen receptor needs binding of estrogen or a drug at its binding spot, and also the binding of any of numerous cofactors at various sites. Without this, the estrogen receptor is not active. Various tissues use different cofactors, and some of these cofactors are able to connect to the estrogen receptor/Clomifen Citrate complex, while others are blocked because of the change in shape. As a result, Clomifen Citrate acts as an antagonist in some tissues. The cofactor used in that tissue is not able to connect, and so the receptor does not become active. In others, Clomifen Citrate works as an activator as the cofactors used in that tissue can bind.

This medication is an effective antagonist in the hypothalamus and in breast tissue. It is an effective agonist in bone tissue, and for improving blood cholesterol levels. It can also reduce the undesirable outcome of muscle tissue pain during activity. This medicine seems to have some effect on mood, which can be helpful. It can improve relationships with women by improving understanding in males taking it. It can also help you with depression.

Follow the recommendation of your doctor when taking Clomifen Citrate. The often-recommended dosage of Clomifen Citrate is 50 mg, taken for five days, on days 3 through 7 of your steroid therapy, or days 5 through 9 of your therapy. Since ovulation and pregnancy rates have been shown to be similar, no matter if you started this medicine on day two, three, four, or five, you should not be worried if your doctor gives you a slightly different prescription.

by: Harry P




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