subject: Acrylamide: Microbiological Method Will Replace The Chemical - Acrylamide - Pharmaceutical [print this page] Create a domestic production of bulk biological Chemical industry Products and materials, first of its kind in the third generation of acrylamide production technology?? Microbe technology, because it has high selectivity, high activity and high efficiency, and produce "waste" less advantages, since inception has been favored. 2009, held last week acrylamide / polyacrylamide industry seminar, national experts predict acrylamide by microbial method will gradually replace the chemical method.
Born, it has been a leading
Acrylamide as a microbiological method for finishing technology, Chinese Academy of Engineering, Zhejiang University of honorary president of ginsenoside head of the establishment of the China's first use of biotechnology in the production of bulk chemicals plant. He said that the currently available production technology of acrylamide by microbial method of countries, only China, Japan, Russia and South Korea four countries. Among them, the level of production technology in China has been leading international. Products using domestic technology is not only good performance, the level of enzyme activity was higher than abroad, but Due to the coupling of free cell separation technology, process is more simple than abroad, less energy consumption. At present, China has overcome a variety of engineering scale technology, production of acrylamide by microbial method ranks first in the world, with a 100,000 tons / year of the largest single set of plant capacity. Moreover, the third generation of acrylamide by microbial method of production process, the Co-ion secondary enzyme-based microbes Shanghai Pesticide Research Institute first isolated from the soil of Mount Tai.
Chinese Academy of Engineering, Nanjing University, Ouyang Kai said, our microbiological method of acrylamide production technology was developed with the use of so far, has always been the forefront of the Habitat International.
Replace only a matter of time
Ouyang said acrylamide by microbial method to create the bulk of domestic production of bio-chemical products, materials, ground, breaking the national high molecular weight, ultra-high molecular weight polyacrylamide production technology and broaden its applications. Can be said that micro-organisms act has "down" the chemical method.
Yin-Chu Shen said that the long term, micro-law would certainly replace the chemical method, this is only a matter of time. Judging from the product purity, chemical acrylamide containing traces of copper and other metal ions, the reaction activity affected to some extent. Microbiological Method Acrylamide not have this problem, a very high reactivity, and reactivity determine the derivatives with acrylamide did reaction speed and yield. As the product of high purity, which aggregate high, especially for the production of "EOR" polyacrylamide. In addition, from a cost point of view, only the consumption of raw materials a, microbial method to great advantage, acrylonitrile unit consumption is 0.76 tons / ton, while the chemical method is 0.82 tons / ton. Tons and above, especially size, its cost advantages will become more apparent.
According to statistics, in 2008 China's production of acrylamide by microbial method accounted for about 43% of the total acrylamide.
Starved for vertical and horizontal development
Yin-Chu Shen pointed out that the microbiological method of acrylamide production process is becoming more mature, in order to expand the application field, in addition to further improve the existing process, but also focus on cross carry out in-depth longitudinal study.
In the longitudinal study, the acrylamide monomer should be applied in different fields, the polymer must be made accordingly. Oil production is relatively simple polymer, wastewater treatment, paper making and other areas of applications are complex, and our technology in this area is still weak. Yin-Chu Shen pointed out that domestic manufacturers are based on existing experience aggregate production, the department has no specific properties of the polymer system of research, therefore, our research in polymer species need to increase investment .
Research in the horizontal, with nitrile compounds are an important class of compounds involved in the field of three enzymes (nitrilase, nitrile hydratase, amidase) of the catalyst. At present the production of acrylamide research in nitrile hydratase progress has been made, if the other two enzymes to in-depth study will be expanded Nitrile compound industry to develop nicotinamide, mandelic acid, - Amino acids , -carboxylic acid, -carboxyl amide and other amide and carboxyl Acids Products. After the relevant universities and research institutes to carry out systematic research, is expected to form the backbone of acrylamide product containing nitrile compounds biotransformation Industry Alliance.
