subject: quot;Generalist" case of technology-coenzyme Q10 production bottlenecks - Coenzyme Q10-Pharma industries [print this page] quot;Generalist" case of technology-coenzyme Q10 production bottlenecks - Coenzyme Q10-Pharma industries
In 2006, the world's Coenzyme Q10 (CoQ10) consumption was 400 500 tons estimated in 2009 the global consumption of about 600 ~ 650 CoQ1O tons, an annual growth rate of 15% to 20%. CoQ10 domestic output of about 50 to 60 tons, while demand in the 80 to 100 tons, larger market gap.
Although our CoQ10 raw material solanesol the world's highest capacity, but are considered coarse products, but the production needs of CoQ10 preparation for more than 90% purity of high purity raw material solanesol. As the raw materials of high purity CoQ10 made not sufficient to supply the needs of domestic manufacturers CoQ10 formulations, many manufacturers from Japan and other developed countries in recent years has been Import CoQ10 preparation of high purity raw material.
In China, CoQ10 health products solanesol semi-synthetic products as raw materials mainly the small number of natural extracts. As the extraction of natural CoQ10 is expensive, mostly for Export .
Applications continue to expand CoQ10 is a natural substance the human body, the biggest role is to protect myocardial cells and prevent fatal heart failure occurred. In 1957, Wisconsin State University professor of biochemistry Flederick? Klein first myocardial cells in experimental animals, isolated pure CoQ10. CoQ10's discovery was hailed as the last century physiology profession 50 years one of the most important biological discovery.
Subsequently, Italy physiological study found: patients with acute heart failure, myocardial cells, CoQ10 levels typically are very small. After several decades, researchers have done a lot of research on CoQ10, found in mitochondria to help fat, carbohydrate and other nutrients into energy, and in maintaining cell membrane function in areas such as flexibility. CoQ10 is also involved in generating a variety of important physiological active substances. Foreign physiologists also believe that: the body has a sufficient amount of CoQ10, can help the body consumes too much fat.
Japan early 80s of last century that is approved for the adjuvant treatment of heart failure embolism CoQ10. From 1976 to the present, the CoQ10 research into the international medical community a "significant learning" and its medical use and health Food Development progress has been held for at least the 8th International Scientific Symposium, foreign scholars agreed that, CoQ10 is a very worthwhile purpose to promote the new health food. Currently, CoQ10 has become a "generalist" of the international best-selling health food.
In the United States, dozens of brand health products CoQ10, the main health demands were: to protect heart health, prevent free radical damage in the body to maintain normal circulation, enhance immunity and anti-aging Class 5. Recently, reports, CoQ10 can be combined with chemotherapy drug to treat multiple malignant disease. This proposal: healthy people often take CoQ10 capsule (day 1) to prevent the occurrence of cancer. CoQ10 newly discovered indications were: blood pressure, prevent age-related macular degeneration, Alzheimer's disease, myocardial infarction, asthma, breast cancer, ventricular expansion, cocaine addiction, anti-HIV / AIDS Increase semen sperm count, anti-migraine, Parkinson's disease, reduce recovery time after surgery, tinnitus patients, Diabetes And Huntington's disease (a congenital genetic disease ataxia) and so on. CoQ10 is a natural physiological active substances, the health-care medicine has broad application prospects.
High purity raw materials to be broken bottleneck
70s in the last century in China began producing CoQ10, was crude extract from pig heart. Early 80s of last century, the country at least a dozen pharmaceutical and biochemical production of porcine heart extract CoQ10.
Japan in early 80s of last century the first to achieve mass production of CoQ10, when using half solanesol synthesis.
