subject: How does Estradiol Valerate (Generic Estrace) work? [print this page] How does Estradiol Valerate (Generic Estrace) work?
How does Estradiol Valerate (Generic Estrace) work?
As per the FDA information, Estradiol Valerate (Generic Estrace) is a basically a female hormone supplement. It is used as oestrogen therapy for bone treatment in aged females. The 17-alpha-isomer of Estradiol binds weakly to oestrogen receptors (receptors, oestrogen) and exhibits little estrogenic activity in oestrogen-responsive tissues. Various isomers can be synthesized.
Side Effects of Estradiol Valerate (Generic Estrace)
Estradiol Valerate is oestrogen supplement that has great risk of developing endometrial cancer in women especially those who have not undergone the hysterectomy. It should be essentially taken with another medication progestin which reduces the risk of developing cancer. A large number of women who took Estradiol Valerate with progestin orally showed that they were more susceptible to heart attacks, strokes, blood clots in lungs, dementia leading to loss of mental capabilities as well as risk of breast cancer.
Guidelines before taking Estradiol Valerate (Generic Estrace)
Estradiol Valerate (Generic Estrace) is recommended to be used only in specific conditions. As oestrogen are known to increase chances of endometrial cancers and breast cancers. It should be used only when you have already tried other products like cream or tablets for vaginal dryness. Moreover, there are several medicines that are safe and effective for treatment of bone loss and should be considered before opting for oestrogen therapy.
What are the common dosages of Estradiol Valerate (Generic Estrace)?
Estradiol Valerate injections are injected by healthcare professionals one every 3-4 weeks in women who do not produce oestrogen hormone naturally. Usually the lowest dose controls the symptoms. Any attempt to taper or discontinue the medication should be done at an interval of 3 months or 6 months. The usual initial dosage range is 1 to 2 mg daily of Estradiol adjusted as necessary to control presenting symptoms.
Difference between Estradiol Valerate and Estrace
Estrace is the generic drug that is available even without the prescription. Estradiol Valerate is available as injections and needs to be taken with the help of a professional health care professional only.
