subject: Everything That You Should Know About Adcirca [print this page] Everything That You Should Know About Adcirca
Primary Pulmonary Hypertension or PPH is a disease that results in fewer than 500 new diagnosis per year, according to Pulmonaryhypertension.in. The website also mentions that the disease causes death of more than 3,000 people every year and a significantly higher number of hospitalizations annually. The problem refers to a rare form of lung disorder, which leads to high blood pressure in the arteries that carry bloods to the lungs. Meanwhile, the blood pressure to the remaining parts of the body remains normal or is sometimes even low. Adcirca (tadafil) has been approved by the FDA for oral administration for treatment of various forms of PPH or Pulmonary Arterial Hypertension (PAH). The drug's effectiveness or safety in children is, however, not known. Role of Adcirca in treatment of Pulmonary Hypertension Adcirca has been indicated for enahancing exercising ability in multiple forms of Pulmonary Arterial Hypertension or PAH patients. These include those suffering from idiopathic and familial PAH as well as PAH associated with scleroderma and congenital heart disease. Pulmonary hypertension can be caused by several factors that include:
Chronic low oxygen levels in the blood
Autoimmune diseases like rheumatoid arthritis and scleroderma that damage the lungs
Certain birth defects in the heart
Some diet medications
History of a blood clot in the lung
HIV infection
Obstructive sleep apnea
Lung or heart valve disease.
Adcirca's main constituent, tadalafil, belongs to a group of medicines called the type 5 inhibitor,s which means that it blocks the PDE5 enzyme found in the blood vessels of the lungs. When this enzyme is blocked, blood vessels in the patient's lungs relax and widene This allows the blood vessels to carry the oxygen rich blood to the rest of the body in a better way. As a result, the heart and lungs no longer have to work hard, which in turn improves the patient's ability to exercise. Adcirca: Dosage and Precautions, The recommended dosage of Adcirca is 40mg (two tablets of 20mg each) once daily. The dosage should not be divided into two parts and should be taken at the same time daily. The most common side effects of this medicine are headache, flushing, nasopharyngitis, nausea, heartburn, stomachache, myalgia, back pain and pain the arms, hands, legs and feet. The drug should, however, never be taken with any nitrate medicines. In case you do that there are chances of your blood pressure dropping quickly to an unsafe level. You get also get dizzy, faint and even have a heart attack or stroke because of this combination.
