subject: Anabolic Enhancement. Do You Know The Risks? [print this page] Anabolic EnhancementAnabolic Enhancement. Do You Know The Risks?
Most serious athletes will tell you that the competitive drive to win can be fierce. Besides the satisfaction of personal accomplishment, athletes often pursue dreams of winning a medal for their country or securing a spot on a professional team. In such an environment, the use of performance-enhancing drugs has become increasingly common.
But using performance-enhancing drugs aka, doping isn't without risks. Take the time to learn about the potential benefits, the health risks and the many unknowns regarding so-called performance-enhancing drugs such as anabolic steroids, androstenedione, human growth hormone, erythropoietin, diuretics, creatine and stimulants. You may decide that the benefits aren't worth the risks.
Anabolic steroids
What are they?
Some athletes take a form of steroids known as anabolic-androgen steroids or just anabolic steroids to increase their muscle mass and strength. The main anabolic steroid hormone produced by your body is testosterone.
Testosterone has two main effects on your body:
Anabolic effects promote muscle building.
Androgenic effects are responsible for male traits, such as facial hair and a deeper voice.
Some athletes take straight testosterone to boost their performance. Frequently, the anabolic steroids that athletes use are synthetic modifications of testosterone. These hormones have approved medical uses, though improving athletic performance is not one of them. They can be taken as pills, injections or topical treatments.
Why are these drugs so appealing to athletes? Besides making muscles bigger, anabolic steroids may help athletes recover from a hard workout more quickly by reducing the muscle damage that occurs during the session. This enables athletes to workout harder and more frequently without overtraining. In addition, some athletes may like the aggressive feelings they get when they take the drugs.
Designer steroids
A particularly dangerous,but extremely effectiveclass of anabolic steroidal agentsare the so-called "designer" drugs synthetic steroids that have been illicitly created to be undetectable by current drug tests. They are made specifically for athletes and have no approved medical use. Because of this, they haven't been tested or approved by the Food and Drug Administration (FDA) and represent a particular health threat to athletes.
Risks
Many athletes take anabolic steroids at doses that are much higher than those prescribed for medical reasons, and most of what is known about the drugs' effects on athletes comes from observing users. It is impossible for researchers to design studies that would accurately test the effects of large doses of steroids on athletes, because giving participants such high doses would be unethical. This means that the effects of taking anabolic steroids at very high doses haven't been well studied.
Anabolic steroids come with serious physical side effects as well.
Men may develop:
Prominent breasts
Baldness
Shrunken testicles
Infertility
Women may develop:
A deeper voice
An enlarged clitoris
Increased body hair
Baldness
Both men and women might experience:
Severe acne
Increased risk of tendinitis and tendon rupture
Liver abnormalities and tumors
Increased low-density lipoprotein (LDL) cholesterol (the "bad" cholesterol)
Decreased high-density lipoprotein (HDL) cholesterol (the "good" cholesterol)
Hypertension
Heart and circulatory problems
Suppression of the hypothalamic-pituitary-gonadal axis
Prostate gland enlargement
Aggressive behaviors, rage or violence
Psychiatric disorders, such as depression
Drug dependence
Infections or diseases such as HIV or hepatitis if you're injecting the drugs
Inhibited growth and development, and risk of future health problems in teenagers
Taking anabolic-androgenic steroids to enhance athletic performance, besides being prohibited by most sports organizations, is illegal. In the past 20 years, more effective law enforcement in the United States has pushed much of the illegal steroid industry into the black market. This poses additional health risks because the drugs are either made in other countries and smuggled in or made in clandestine labs in the United States. Either way, they aren't subject to government safety standards and could be impure or mislabeled.
Androstenedione
What is it?
Androstenedione (andro) is a hormone produced by the adrenal glands, ovaries and testes. It's a hormone that's normally converted to testosterone and estradiol in both men and women.
Andro is available in prescription and nonprescription forms. The prescription version is a controlled substance. Andro is also sold without a prescription as a nutritional supplement. Manufacturers and bodybuilding magazines tout its ability to allow athletes to train harder and recover more quickly. However, its use as a performance-enhancing drug is illegal in the United States.
Scientific studies that refute these claims show that supplemental androstenedione doesn't increase testosterone and that your muscles don't get stronger with andro use. In fact, almost all of the andro is rapidly converted to estrogen, the primary hormone in females.
Risks
Side effects of andro in men include:
Acne
Diminished sperm production
Shrinking of the testicles
Enlargement of the breasts
In women, side effects include:
Acne
Masculinization, such as deepening of the voice and male-pattern baldness
In both men and women, andro can decrease HDL cholesterol (the "good" cholesterol), which puts you at greater risk of heart attack and stroke.
Human growth hormone
What is it?
Human growth hormone, also known as gonadotropin, is a hormone that has an anabolic effect. Athletes take it to improve muscle mass and performance. However, it hasn't been shown conclusively to improve either strength or endurance. It is available only by prescription and is administered by injection.
Risks
Adverse effects related to human growth hormone range in severity and may include:
Joint pain
Muscle weakness
Fluid retention
Carpal tunnel syndrome
Impaired glucose regulation
Cardiomyopathy
Hyperlipidemia
The bottom line
Do performance-enhancing drugs boost performance? Some athletes may appear to achieve physical gains from such drugs, but at what cost? The long-term effects of performance-enhancing drugs haven't been rigorously studied. And short-term benefits are tempered by many risks. Not to mention that doping is prohibited by most sports organizations. No matter how you look at it, using performance-enhancing drugs is risky business.
