subject: Enteric Coating Materials - Properties & Advantages [print this page] Different types of tablets are manufactured in different ways. But, nowadays, modern contract manufacturing companies or encapsulation specialists have been making use of enteric coating materials due to various reasons.
It is essential for tablets components to get released in the intestinal region or when enters into the duodenum. Moreover, the method is essential to get used for drugs which cause gastric irritation.
In this article, well come to know more about the enteric coating material, reasons of the application, properties and much more.
Important reasons are as follows:
Protection
The first reason is to protect acid-liable drugs from the harmful gastric fluid like certain antibiotics and enzymes. It is also used to prevent nausea or gastric distress due to irritation from the drug like sodium salicylate and much more.
Avoid irritation
Direct release of components of drugs into the stomach can led one to face gastric irritation and other problems. Considering this, companies have been making use of enteric coating material to avoid irritation problems in stomach. Enteric coating tablets are thus getting produced to let one use the drugs without worry of irritation.
Now, lets check the properties of enteric coating material.
Resistance and susceptibility
The enteric coated material is known to come with the feature of resistance to gastric fluids. Adding to it, the tablets are considered susceptible or permeable to intestinal fluids.
Stability and compatibility
The materials are known to be compatible with most drug substrates and coating solution components. The tablet films should not change on the factor of aging. One should know that the enteric coating materials are known to be stable for years when stored in a dry and cool place.
Low cost and non-toxicity
The enteric coating tablets available with the companies are available with non-toxicity features and with low cost as well. The quality experts of the firm check the composition and other component details of the tablets to confirm the non-toxicity factor and other.
After being in prolonged contact with acidic gastric fluids, they get dissolve easily in the mildly acidic to neutral environment of the small intestine. When they are stored at high humidity and high temperature, enteric coating material slowly hydrolyze and thus increase the free acidic content.
Thus, from the discussions, one can easily come to know about the properties of enteric coating tablets and why they are getting produced by modern encapsulation specialists and other leading contract manufacturers.
