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subject: Softgel capsule Benefits in natural health and pharmaceutical products [print this page]


Soft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption and enhancing bioavailability of both insoluble and lipid-soluble compounds. In addition, soft gels offer many other key advantages and therapeutic benefits:

Ease of Swallowing

Convenience

Acceptability

Dosage Accuracy

Uniformity and precision dosageSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption.

Adaptability

LiquidSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption and enhancing bioavailability of both insoluble and lipid-soluble compounds.

Semi-solids

Suspension

Emulsion

Product Security

Dosage and formulation are tamper-resisSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorptiontant (a punctured or tampered softgels will leak or become discoloured)

Protection against counterfeit

Product StabilitySoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption

Sealed container

Protection from light for photosensitive formulations

Masking of objectionable odors and tastes

Protects drug from oxidation and degradation

Market Differentiation

Size, shape and colour customizationSoftgel capsule Benefits in natural health and pharmaceutical products

Soft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption and enhancing bioavailability of botSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption and enhancing bioavailability of both insoluble and lipid-soluble compounds.h insoluble and lipid-soluble compounds.Imprintability of capsulesSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption

Softgel technology

Softgel benefits of Biological and marketing advantage:

Better protection of active ingredientshermetically sealed dosage form protects drug from oxidation and degradation.

Improved absorption and bioavailability any formulations in softgel can enhance bioavailability or produce a quicker onset ofSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption and enhancing bioavailability of both insoluble and lipid-soluble compounds. action.

Marketplace differentiationa nearly endless array of shapes, sizes and shell colors helps your product stand out from branded or generic competitors.

Consumer preferenceresults of studies done through the years show that consumers expressed their preference for softgels in terms of ease of swallowing, perceived speed of delivery, lack of unpleasant odor or taste, and modern appearance.

Tamper evidencea punctured or otherwise tampered softgel will leak or become discolored, indicating a potential problem.

Formulation characteristics:

Self-emulsifying/microemulsion vehicle systems

Liquid (solution or suspension) fillsSoftgel Vitamin Manufacturing

Wide range of softgel-compatible vehicles (hydrophilic/lipophilic)

Virtually unlimited selection of shapes, sizes and colors

Unique formulations leading to patentable line extensions

New technologies, including innovative shell forms and manufacturing techniques

Key advantages:

Enhanced bioavailability

Minimizes patient-to-patient variability

Possible lowered drug dosing

Excellent dose uniformity

Obvious evidence of tampering

Ability to solubilize a wide range of active ingredientSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption and enhancing bioavailability of both insoluble and lipid-soluble compounds.s

Maximizes drug loading

Extensive product differentiation possibilities

Enhanced life-cycle managementSoft gels or soft gelatin capsules provide an ideal drug delivery vehicle for controlling absorption and enhancing bioavailability of both insoluble and lipid-soluble compounds.

By Nutralab Canada Ltd. ( www.nutralab.ca)

Softgel capsule Benefits in natural health and pharmaceutical products

By: David Backham




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