subject: Stability Personified Generic Depakote [print this page] The generic name for the drug Depakote is Valproic Acid, Divalproex Sodium and Sodium Valproate. The active e ingredient in the drug is Valproic acid. This drug received approval from the American authorities in 1978. It is used to treat patients with epileptic seizures, maniac depression or bipolar disorder as also migraine headaches. The drug is also known and sold as Depakene, Depacon Depakote ER and Divalproex.
Doctors prescribe this drug to stabilize the mood of the patient. Depakote acts by affecting the Gamma-amino butyric acid in the brain. This chemical also known as GABA is used by the nerves to communicate with each other. Depakote is available in various forms like capsules and tablets of differing dosage strengths from 125 mg to 500 mg. Other forms of Depakote available in the market are sprinkles syrups and even injections. In every 5ml of the syrup the content of Valproic acid is 250 mg and every 5 ml of injection contains 1000 ml of the drug.
A patient suffering from epileptic seizures starts with a low dosage of 10 to 15 mg per kg of body weight and the doctor slowly increases the dosage till the Valproic acid in the blood reaches the level of 50 to 100 mcg per ml. while patients suffering from bipolar disorder start with a high dosage of 750 mg, those treated for migraine headaches with Depakote have a dosage of 250mg twice daily of delayed release tablets to start with.
Depakote should not be used by pregnant women as it affects the fetus and the baby will be born with congenital cardio vascular problems, spina bifida as also neural tube defects. Depakote also reduces platelet count thus leading to the inability of the blood to clot as also abnormal bleeding.
While taking Depakote patients should consult their doctor if they encounter side effects like mild abdominal cramps, constipation or diarrhea, indigestion or loss of appetite, unusual weight gain or weight loss. Women may experience menstrual cycle changes as well.
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