subject: Edible Vaccines [print this page] Vaccines have been used revolutionary for the prevention of infectious diseases. Edible vaccines or Food Vaccine hold great promise as an easy-to-administer, cost-effective, easy-to-store, and socioculturally willingly acceptable vaccine delivery system, particularly for the developing countries like India. Edible vaccines offer exciting opportunities for significantly reducing the burden of diseases like hepatitis, cholera & measles, mainly in the developing world where the administrating & storage of vaccines is at major concern. Edible Vaccines are prepared by molecular farming with the help of genetic engineering. Preparation of Edible Vaccines are involving the introduction of selected desired genes into plants and inducing these genetically modified plants to manufacture the encoded proteins. This process is known as transformation and the altered plants are called transgenic plants. These are mucosal targeted vaccines, which causes systemic & mucosal immune response stimulation. Edible vaccines are also being helpful to suppress the autoimmune disorders like diabetes mellitus-type I, diarrhoea, multiples sclerosis and rheumatoid arthritis. There is growing acceptance of transgenic crops in both industrial and developing countries. Edible vaccines provides huge platform to unfold the treatment of many disease. This review is a conceptual framework to study the preparation, mode of action, current development, clinical trail & application of Edible Vaccines. Creating edible vaccines involves introduction of selected desired genes into plants and then inducing these altered plants to manufacture the encoded proteins. This process is known as "transformation," and the altered plants are called "transgenic plants." Like conventional subunit vaccines, edible vaccines are composed of antigenic proteins and are devoid of pathogenic genes
