subject: Visit The "china [print this page] Ion chromatography pioneer in China " Ion chromatography pioneer in China "
? Visit Ecological Environment Research Center Chinese Academy of Sciences researcher Mou
1975 H. Small, who successfully solved the continuous detection column conductivity detector effluent problem, created by ion chromatography, inorganic ions to achieve a rapid separation and detection, so that ion chromatography (IC) as liquid chromatography Technology A branch of the rapidly developed, the same year came the first commercial IC instrument. With the development of domestic ion chromatography, China has independently developed the first generation of commercial ion Chromatography Also successfully launched in 1984. Experienced nearly 30 years of development, ion chromatography with the application of demand-driven, increasingly strong development momentum.
Mou researchers in the field of ion chromatography applications based on nearly three decades of painstaking research, has undertaken and presided over the "Eighth Five-Year" and the "Ninth Five-Year" national key research project on "Development and Application of Ion Chromatography Development" and the International Cooperation Topic "Application of ion chromatography for basic research," and so on. Soluble organic compounds in water by ion chromatography analysis of studies of trace components in complex matrices by ion chromatography analysis research, and without pre-column and post-column derivatization reaction of carbohydrates and amino acids such as direct analysis of the research results, in aroused the attention of international counterparts. And won the "subject of ion chromatography have made outstanding contributions to the international award" honors.
Days ago, I had the honor to CAS Ecological Environment Research Center of Environmental Chemistry and Ecotoxicology International Laboratory on "Advances in ion chromatography, ion chromatography standard construction, and domestic development of ion chromatography business," so on an exclusive interview Mou researcher.
Ion chromatography in the ascendant Interview Opening, Mou researchers described the advantages of ion chromatography: "First of all, ion chromatography is a short carbon chain organic acid anions and the preferred method of analysis; Secondly, many compounds do not absorb light group, not suitable for UV detection, detection is required by high performance liquid column only after post-column derivatization UV detection, in addition to a number of compounds not suitable derivative Reagent To have absorption groups, but the polarity and water solubility of these compounds are stronger this time because of its unique advantage of ion chromatography to solve such problems, a conventional means of analytical chemistry; Finally, the basic need of organic ion chromatography solvent (generally organic solvents are more toxic), using the process safety Environmental protection . "
Talk about technology and Application of ion chromatography, the Mou researchers on the following points:
(1) continuously expanding range of applications
With the rising market demand and the development of ion chromatography, ion chromatography in the field more and more widely. As in recent years, one of the fastest growing analytical techniques, ion chromatography applications ranging from common anions and cations and organic acids, development to its different oxidation states of transition metals, water soluble polar organic compounds, amino acid and sugar compounds, have been widely applied in environmental, Food , Agriculture, energy, water, semiconductors, biomedical and other fields of routine testing and scientific research. "International Ion Chromatography Expert PRHaddad said: Biochemical analysis of ion chromatography in the future will be a very promising development directions. Ion chromatography has become a more mature analysis techniques, but with new materials, new technologies, ion chromatography will still have a very broad space for development. "
(2) the escalating R & D
Ion chromatography column on technology development, Mou researchers emphasized: "ion chromatography method is selective and depends on the stationary phase is what we always said the column?? Ion Chromatography 'heart'. In recent years various column technology has developed rapidly, and the HPLC column of the main differences are: most of the matrix is silica gel HPLC column, and ion chromatography column for the organic polymer matrix more suitable for wide range of pH, as a routine analysis method, to use more convenient. "
Current research focuses on ion column: a new ion exchange column packing; efficient high-volume column, monolithic column, rapid column and high-selectivity columns.
IC technology combined with AAS, AFS, ICP-MS and MS, etc. in recent years combined with another hot IC application development. Such as IC and atomic fluorescence spectrometry, for arsenic, mercury, selenium, chromium valence and speciation analysis; suppressed IC with MS, MS, for complex-based analysis of trace elements to improve the methods selectivity and sensitivity. DR
small ion chromatography, capillary ion chromatography and ion chromatography microchip miniaturization ion chromatograph, ion chromatography is the latest development in international hot spots, but the country has rarely.
Reagent free ion chromatography and virtual column "The United States Dianne's latest reagent free ion chromatography (RFIC-EG and RFIC-ER), RFIC-EG-line only produces high purity water eluent such concentrations can be gradient elution pump, so that the development of methods is very convenient; as only water through the pump and reduce pollution of the pump, extend the pump life. RFIC-ER are washing line automatic regeneration, a cream formulated 4L lotion can be used continuously for 4 weeks, only to make a calibration curve. RFIC technology comprehensively improve the efficiency of ion chromatography to analyze workers to take time and effort to make deeper and broader research. "
"International Ion Chromatography very respected expert PRHaddad chromatographic conditions can be screened for 'virtual pillar' software, the computer simulation method to simulate the conditions for a suitable, feasible suggestions for chromatography workers to avoid unnecessary attempts, greatly improving efficiency. "
Ion chromatography standards development in several issues
"Standard method should have the versatility, accuracy, we can approach the text to make the right results. Standard method of comparison with foreign countries, our standard method of ion chromatography write simpler, more general scope, column product model is not clear, is generally not recommended to use mass spectrometry and other issues not conducive to the effective widespread use of standard methods. "
