subject: Etiology Of Plantar Warts [print this page] Plantar warts occur most frequently in children and young adults. Plantar warts are epidermal lesions caused by an infection by the human papilloma virus (HPV). These are usually encountered on the soles of the feet. Unfortunately, these grow inward, often resulting in a painful hard lump. It is not uncommon for these to have black spots in the center.
Plantar warts causes significant pain from just standing and walking, and so is a type that demands an immediate and fast-acting wart cure. Almost 200 strains of HPV have been identified. The subtypes commonly found in plantar warts are HPV 1, 2, 4 and 10. More strains seem to be discovered year by year, creating a huge challenge for warts cure treatments.
The HPV virus is transmitted between hosts through direct contact. For infection and replication to take place, the virus requires a compromised skin surface with epithelial cells in an advanced state of differentiation. The virus attacks the granulosum and keratin layers of the epidermis. The viral DNA and protein production occur in the upper spinous layer with final virus assembly occurring in the granular layer.
HPV is a non-enveloped, double-stranded DNA virus that replicates in all epithelial cell layers. However, viral replication is associated with excessive proliferation of all of the epidermal layers except the basal layer. This process produces acanthosis, parakeratosis and hyperkeratosis. There is also a deepening of the rete ridges, which produces the typical papillomatous architecture that produces pinpoint bleeding with debridement of the lesion.
One study suggests that the persistence of disease may be attributable to a lack of Langerhans cells at the site of the lesion, leading to decreased stimulation of cell-mediated immune response. Minor trauma at the site of inoculation may be important as there could be an abrasion of the skin that allows penetration of the wart into the epidermis. Warts will frequently be present in high-pressure or high-friction areas that are often otherwise occupied by calluses.
Though one can diagnose warts with a high degree of certainty based on their clinical appearance, a biopsy may be required for a definitive diagnosis. If a lesion is chronic, aggressive, irregular and resistant to multiple therapies, be cautious of possible malignancy. In rare cases, warts may degenerate into verrucous carcinomas.
Warts are classically treated with topical acid, or by freezing the tissue with liquid nitrogen. Freezing causes a blister, and as the blister heals the wart will hopefully come off with it. However, these cures for warts are not always successful. In fact, warts may recur after using a common wart cure because of the activation of latent virus present in healthy skin adjacent to the lesion.
Most patients with warts require multiple warts cure treatments over a course of several weeks or months. If substantial improvements have not occurred after 3 physician-administered treatments or if complete clearance has not occurred after 6 treatments, a different treatment modality should be used.
For warts, cures used to treat HPV disease are applied topically on cutaneous surfaces. Local skin reactions and pain are common adverse effects. More difficult warts may have to be surgically excised or burned off. Once surgical intervention or chemical acids are used one can expect a scar in that area.
AntiWarts-Rx is a potent anti-viral agent for topical use against warts. It inhibits and kills the HPV virus, resulting in fast elimination of warts and wart like substances. The antiviral properties in AntiWarts-Rx are highly pronounced and well documented. They quantifiably destroy the HPV virus, thus characterizing AntiWarts-Rx as a potent anti warts agent.
As a result, it is no surprise that the antiviral compounds in AntiWarts-Rx are used by drug companies to manufacture pharmaceutical treatments for genital warts, warts, and cancer. AntiWarts-Rx is composed of naturally occurring high intensity antiviral extracts which have a lethal effect against warts upon exposure.
Application of AntiWarts-Rx provides maximum and rapid penetration of antiviral agents into cell membranes without damaging healthy tissue. As a result, this treatment enjoys a well earned reputation for its curative effects against warts. To learn more, please go to http://www.naturespharma.org.
