subject: Aarkstore Enterprise--- Rna Interference Markets-biotechnology, Healthcare And Life ... [print this page] Table of Contents : Table of Contents :
1 Overview 7
1.1 Objectives 7
1.2 Scope 7
1.3 Methodology 9
1.4 Executive Summary 10
2 RNA Interference (RNAi) 13
2.1 Introduction 13
2.2 Overview of RNA Interference 13
2.2.1 Classes of Endogenous Small RNAs: siRNA, rasiRNA and miRNA 14
2.2.2 Mechanism of RNAi In Vivo 15
2.3 Glossary 18
2.4 What Areas of Research Does RNAi Impact? 19
2.4.1 RNAi Technology in Life Sciences Research, Drug Discovery and Development 20
2.4.2 RNAi Technology in Agriculture 26
3 Technology Trends in RNAi Space 29
3.1 Overview 29
3.2 End-User Segmentation 29
3.3 Technologies for Inducing RNAi 30
3.3.1 Methods for Detecting Gene Silencing 31
3.3.2 Comparison of Strategies for Target Validation 32
3.3.3 Libraries of siRNAs/shRNAs to Knock Down Genes En Masse 32
3.4 miRNA-Based RNAi: The Leading Edge of RNAi Space 38
3.4.1 Biological Function of miRNAs 39
3.4.2 Role of miRNAs in Disease 40
3.4.3 miRNA-based Diagnostics 44
3.4.4 miRNA-based Therapeutics 46
3.5 Market Shifts in RNAi Space: Where Is It Headed? 47
3.5.1 Intellectual Property and Patent Issues 48
3.5.2 Patents Covering the Molecular Characteristics of the RNAi Agent 48
3.5.3 Funding in RNAi Space: Grants, Venture Capital and IPOs 50
3.5.4 Partnerships, Alliances, Mergers and Acquisitions 51
3.6 SWOT Analysis of Technologies and Vendors in RNAi Space 53
4 RNAi Market Analysis 56
4.1 Overview 56
4.2 Market Data Collection and Respondent Pool 56
4.2.1 Respondent Pool Characteristics 56
4.3 RNAi Technologies / Products in Research Applications 58
