Christian Louboutin Export Induced

Yip1A depletion led to restructuring of the network into multiple

, micrometer-sized Christian Louboutin Bat Girl 100 shoes whorls. Membrane stacking and whorl formation coincided with a marked slowing of coat protein (COP) II-mediated protein export. Furthermore, whorl formation driven by exogenous expression of an ER protein with no role in COPII function also delayed cargo export. Thus, the slowing of protein export induced by Yip1A depletion may be attributed to a proximal role for Yip1A in regulating ER network dispersal.

2010 JUN 29 - ( NewsRx.com) -- "The Christian Louboutin Bicho Striped Suede Pump of the endoplasmic reticulum (ER) undergoes highly regulated changes in specialized cell types (see also Organelles). One frequently observed type of change is its reorganization into stacked and concentrically whorled membranes, but the underlying mechanisms and functional relevance for cargo export are unknown," investigators in the United States Christian Louboutin black almond toe sandals.

"Here, we identify Yip1A, a conserved membrane protein that cycles between the ER and early Golgi, as a key mediator of ER organization. Yip1A depletion led to restructuring of the network into multiple, micrometer-sized concentric whorls. Membrane stacking and whorl formation coincided with a marked slowing of coat protein (COP) II-mediated protein export. Furthermore, whorl formation driven by exogenous expression of an ER protein with no Christian Louboutin black cutout sandles 1 in COPII function also delayed cargo export.

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