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Drug

Etymology

Etymology

Drug is thought to originate from Old French "drogue", possibly deriving later into "droge-vate" from Middle Dutch meaning "dry barrels", referring to medicinal plants preserved in them.

Medication

Nexium pills 40 mg

(esomeprazole magnesium)

Main article: pharmaceutical drug

A medication or medicine is a drug taken to cure and/or ameliorate any symptoms of an illness or medical condition, or may be used as preventive medicine that has future benefits but does not treat any existing or pre-existing diseases or symptoms.

Dispensing of medication is often regulated by governments into three categoriesver-the-counter (OTC) medications, which are available in pharmacies and supermarkets without special restrictions, behind-the-counter (BTC), which are dispensed by a pharmacist without needing a doctor's prescription, and Prescription only medicines (POM), which must be prescribed by a licensed medical professional, usually a physician.[citation needed]

In the United Kingdom, BTC medicines are called pharmacy medicines which can only be sold in registered pharmacies, by or under the supervision of a pharmacist, these medications are designated by the letter P on the label, the precise distinction between OTC and prescription drugs depends on the legal jurisdiction.[citation needed]

Medications are typically produced by pharmaceutical companies and are often patented to give the developer exclusive rights to produce them, but they can also be derived from naturally occurring substance in plants called herbal medicine.[citation needed] Those that are not patented (or with expired patents) are called generic drugs since they can be produced by other companies without restrictions or licenses from the patent holder.

Drugs, both medicinal and recreational, can be administered in a number of ways:

Orally, as a liquid or solid, that is absorbed through the stomach.

Sublingually, diffusing into the blood through tissues under the tongue.

Inhaled, (breathed into the lungs), as a vapor.

Injected as a liquid either: intramuscular, intravenous, intraperitoneal, intraosseous.

Rectally as a suppository, that is absorbed by the colon.

Vaginally as a suppository, primarily to treat vaginal infections.

Bolus, a substance into the stomach to dissolve slowly.

Insufflation, or snorted into the nose.

Many drugs can be administered in a variety of ways.

Recreation

The cigarette is the common pharmaceutical form of tobacco one of the world best selling drugs.

Cannabis is another commonly used recreational drug.

Main article: Recreational drug use

Further information: Prohibition (drugs)

Recreational drugs use is the use of psychoactive substances to have fun, for the experience, or to enhance an already positive experience. National laws prohibit the use of many different recreational drugs and medicinal drugs that have the potential for recreational use are heavily regulated. Many other recreational drugs on the other hand are legal, widely culturally accepted, and at the most have an age restriction on using and/or purchasing them. These include alcohol, tobacco, betel nut, and caffeine products.

Spiritual and religious use

Main article: Entheogen

The spiritual and religious use of drugs has been occurring since the dawn of our species. Drugs that are considered to have spiritual or religious use are called entheogens. Some religions are based completely on the use of certain drugs. Entheogens are mostly hallucinogens, being either psychedelics or deliriants, but some are also stimulants and sedatives.

Nootropics

Main article: Nootropic

Nootropics, also commonly referred to as "smart drugs", are drugs that are claimed to improve human cognitive abilities. Nootropics are used to improve memory, concentration, thought, mood, learning, and many other things. Some nootropics are now beginning to be used to treat certain diseases such as attention-deficit hyperactivity disorder, Parkinson's disease, and Alzheimer's disease. They are also commonly used to regain brain function lost during aging.

Legal definition of drugs

Some governments define the term drug by law. In the United States, the Federal Food, Drug, and Cosmetic Act definition of "drug" includes "articles intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in man or other animals" and "articles (other than food) intended to affect the structure or any function of the body of man or other animals." Consistent with that definition, the U.S. separately defines narcotic drugs and controlled substances, which may include non-drugs, and explicitly excludes tobacco, caffeine and alcoholic beverages.

Governmental controls

The examples and perspective in this article may not represent a worldwide view of the subject. Please improve this article and discuss the issue on the talk page. (November 2009)

In Canada the government has moved to remove the influence of drug companies on the medical system.[citation needed] he influence that the pharmaceutical companies, the for-profits, are having on every aspect of medicine ... is so blatant now you'd have to be deaf, blind and dumb not to see it, said Journal of the American Medical Association editor Dr. Catherine DeAngelis.

See also

Pharmacy and Pharmacology portal

Drug abuse

Drug addiction

Drug development

Drug injection

Generic drug

Illegal drug trade

Lifestyle drug

List of drugs is an extensive alphabetical list of drugs by name.

Narcotics

Pharmaceutical drug

Placebo (origins of technical term)

Prescription drug

Prodrug

Psychedelic plants

Psychoactive drug

Recreational drug use

Responsible drug use

War on Drugs

References

^ Deutscher Kaffeeverband (2001-05-04). "Kaffee-Text 1/99" (in German) (PDF). http://www.kaffeeverband.de/pdf/kt1-99.pdf. Retrieved 2007-12-14.

^ In Germany about 118 of beer, 20 of wine, 4 of sparkling wine and 6 of distilled beverages are consumed per person per year.[citation needed]

^ World Health Organization. (1969). WHO Expert Committee on Drug Dependence. Sixteenth report. (Technical report series. No. 407).Geneva:World Health Organization.

^ a b "Drug." Dictionary.com Unabridged (v 1.1), Random House, Inc., via dictionary.com. Retrieved on 20 September 2007.

^ a b c "Drug." The American Heritage Science Dictionary, Houghton Mifflin Company, via dictionary.com. Retrieved on 20 September 2007.

^ a b "Drug." Merriam-Webster's Medical Dictionary, Merriam-Webster, Inc., via dictionary.com. Retrieved on 20 September 2007.

^ Harper, Douglas. "drug". Online Etymology Dictionary. http://www.etymonline.com/index.php?term=drug.

^ "Glossary of MHRA terms - P". MHRA. http://www.mhra.gov.uk/SearchHelp/Glossary/GlossaryP. Retrieved 2008-11-05.

^ According to the statistic of the Food and Agriculture Organization the production quantity in 2006 of coffee was 7.8 million tonnes and of tobacco was 6.7 million tonnes.

^ Lingeman, Drugs from A-Z A Dictionary, Penguin ISBN 0 7139 0136 5

^ "Federal Food, Drug, and Cosmetic Act" (Website.) U.S. Food and Drug Administration. Retrieved on 24 September 2007.

^ "21 USC Sec. 802." (Website.) U.S. Department of Justice. Retrieved on 24 September 2007.

^ "Med schools, journals fight big pharma's sway" (Website.) MSNBC. Retrieved on 11 November 2009

^ "Medical schools, journals start to fight drug industry influence" (Website.) USA Today. Retrieved on 11 November 2009

External links

The Cult of Pharmacology: How America Became the World's Most Troubled Drug Culture by Richard DeGrandpre, Duke University Press, 2006.

'don't drug + drive' German web-site providing information on the influence of recreational drugs in driving.

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Pharmacology: Major drug groups

Gastrointestinal tract/metabolism (A)

stomach acid (Antacids, H2 antagonists, Proton pump inhibitors) Antiemetics Laxatives Antidiarrhoeals/Antipropulsives Anti-obesity drugs Anti-diabetics Vitamins Dietary minerals

Blood and blood forming organs (B)

Antithrombotics (Antiplatelets, Anticoagulants, Thrombolytics/fibrinolytics) Antihemorrhagics (Platelets, Coagulants, Antifibrinolytics)

Cardiovascular system (C)

cardiac therapy/antianginals (Cardiac glycosides, Antiarrhythmics, Cardiac stimulants)

Antihypertensives Diuretics Vasodilators Beta blockers Calcium channel blockers renin-angiotensin system (ACE inhibitors, Angiotensin II receptor antagonists, Renin inhibitors)

Antihyperlipidemics (Statins, Fibrates, Bile acid sequestrants)

Skin (D)

Emollients Cicatrizants Antipruritics Antipsoriatics Medicated dressings

Reproductive system (G)

Hormonal contraception Fertility agents SERMs Sex hormones

Endocrine system (H)

Hypothalamic-pituitary hormones Corticosteroids (Glucocorticoids, Mineralocorticoids) Sex hormones Thyroid hormones/Antithyroid agents

Infections and infestations (J, P, QI)

Antibiotics (Antimycobacterials) Antifungals Antivirals Antiparasitics (Antiprotozoals, Anthelmintics) Ectoparasiticides Intravenous immunoglobulin Vaccines

Malignant disease (L01-L02)

Anticancer agents (Antimetabolites, Alkylating, Spindle poisons, Antineoplastic, Topoisomerase inhibitors)

Immune disease (L03-L04)

Immunomodulators (Immunostimulants, Immunosuppressants)

Muscles, bones, and joints (M)

Anabolic steroids Anti-inflammatories (NSAIDs) Antirheumatics Corticosteroids Muscle relaxants Bisphosphonates

Brain and nervous system (N)

Analgesics Anesthetics (General, Local) Anorectics Anti-ADHD Agents Antiaddictives Anticonvulsants Antidementia Agents Antidepressants Antimigraine Agents Antiparkinson's Agents Antipsychotics Anxiolytics Depressants Entactogens Entheogens Euphoriants Hallucinogens (Psychedelics, Dissociatives, Deliriants) Hypnotics/Sedatives Mood Stabilizers Neuroprotectives Nootropics Neurotoxins Orexigenics Serenics Stimulants Wakefulness-Promoting Agents

Respiratory system (R)

Decongestants Bronchodilators Cough medicines H1 antagonists

Sensory organs (S)

Ophthalmologicals Otologicals

Other ATC (V)

Antidotes Contrast media Radiopharmaceuticals Dressings

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Recreational drug use

Major Recreational Drugs

Cannabinoids

THC (Cannabis Hashish Hash oil)

Depressants

Barbiturates Benzodiazepines Ethanol (Alcoholic beverages) GHB Nonbenzodiazepines Kava

Entactogens

MDA MDMA (Ecstasy)

Hallucinogens

Psychedelics

Bufotenin (Yopo Vilca Psychoactive toads) DMT (Ayahuasca) LSD-25 Mescaline (Peyote San Pedro Peruvian Torch) Psilocybin & Psilocin (Psilocybin mushrooms)

Dissociatives

DXM Inhalants (Nitrous oxide) Ketamine PCP Salvinorin A (Salvia divinorum)

Deliriants

Datura Deadly Nightshade Henbane Mandrake

Opioids

Codeine Diacetylmorphine Hydrocodone Morphine (Opium) Oxycodone Kratom

Stimulants

Amphetamine Arecoline (Areca) Betel Caffeine (Coffee - Tea) Cathinone (Khat) Cocaine (Coca) Ephedrine (Ephedra) Methamphetamine Methylphenidate Nicotine (Tobacco) Theobromine (Cocoa)

Culture and Related Topics

Cannabis

420 Stoner Film Spiritual Use of Cannabis Medical Cannabis Cannabis Cultivation Cannabis smoking

Psychedelic

Art Drug Experience Literature Music

Other

Counterculture of the 1960s Club Drug Dance Party Drug Tourism Drug Paraphernalia Hippie Party and Play Poly Drug Use Rave Sex and Drugs Spiritual use of drugs

Problems with Drug Use

Abuse Addiction (Prevention Rehabilitation Responsible Use) Illegal Trade Overdose

Legality of Drug Use

International

1961 Narcotic Drugs 1971 Psychotropic Substances 1988 Drug Trafficking

State Level

Drug Policy (Prohibition Decriminalization) Policy Reform (Liberalization Harm Reduction Demand Reduction)

Other

Designer Drug Drug Possession Drug Test Hard and Soft Drugs Narc War on Drugs

Lists of Countries by...

Alcohol Consumed Cannabis Legality (Annual Use Lifetime Use) Cocaine Use Opiate Use Tobacco Smoked

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Depressants

Antihistamines

H1R Antagonists

1st Generation

Dimenhydrinate Diphenhydramine Doxylamine Hydroxyzine Promethazine ...

Others

Amitriptyline Doxepin Mianserin Mirtazapine ...

Antipsychotics

Mixed MOA

Typicals

Chlorpromazine Haloperidol ...

Atypicals

Aripiprazole Clozapine Olanzapine Quetiapine Risperidone Ziprasidone ...

Channel Blockers

Carbamazepine Ethosuximide Gabapentin Lamotrigine Oxcarbazepine Phenytoin Pregabalin Topiramate Zonisamide

Dissociatives

NMDAR Antagonists

Arylcyclohexylamines

Esketamine Dieticyclidine Eticyclidine Gacyclidine Ketamine Phencyclidine Rolicyclidine Tenocyclidine Tiletamine

Morphinans

Dextromethorphan / Methorphan Dextrorphan / Morphanol

Others

Dexoxadrol Dizocilpine (MK-801) Etoxadrol Nitrous Oxide Selfotel Xenon ...

GABAergics

Barbiturates

Amobarbital Pentobarbital Phenobarbital Secobarbital ...

Benzodiazepines

Alprazolam Chlordiazepoxide Clonazepam Diazepam Lorazepam ...

Carbamates

Carisoprodol Felbamate Meprobamate ...

GABA Analogues

1,4-BD Aceburic Acid Gabaculine GBL GABA GABOB GHB GHV GVL Isovaleramide Isovaleric Acid Phenibut Picamilon Tiagabine Valeric Acid Valerenic Acid Valnoctamide Valproic Acid (Sodium Valproate / Valproate Semisodium) Valpromide Vigabatrin

Neuroactive Steroids

Alfaxalone Allopregnanolone Ganaxolone Tetrahydrodeoxycorticosterone ...

Nonbenzodiazepines

Eszopiclone Zaleplon Zolpidem Zopiclone ...

Piperidinediones

Glutethimide ...

Propylphenols

Fospropofol Propofol Thymol

Quinazolinones

Methaqualone ...

Others

Baclofen Clomethiazole Diethyl Ether Ethanol (Alcohol) Etomidate Gaboxadol Muscimol Stiripentol Theanine Kavalactones (Kava Kava) Valerenic Acid (Valerian)

Glycinergics

Alanine Cycloserine Dimethylglycine Glycine Hypotaurine Methylglycine / Sarcosine Serine Taurine Trimethylglycine / Betaine

Narcotics

MOR Agonists

Opiates

Opium Codeine Morphine Oripavine Thebaine

Opioids

Alfentanil Buprenorphine Butorphanol Carfentanil Diacetylmorphine (Heroin) Dihydrocodeine Ethylmorphine Etorphine Fentanyl Hydrocodone Hydromorphone Ketobemidone Levacetylmethadol Levorphanol Meperidine / Pethidine Methadone Nalbuphine Oxycodone Oxymorphone Pentazocine Phenazocine Propoxyphene Remifentanil Tapentadol Tramadol Sufentanil

Others

Kratom

Sympatholytics

/-AR Modulators

Alpha Blockers

Doxazosin Phentolamine Prazosin Tamsulosin Urapidil ...

Beta Blockers

Propranolol ...

Others

Clonidine ...

Miscellaneous

Chloroform Cyclobenzaprine Trazodone ...

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Hallucinogens

Psychedelics

5-HT2AR Agonists

Lysergamides: AL-LAD ALD-52 BU-LAD CYP-LAD DAM-57 Diallyllysergamide Ergometrine (Ergonovine, Ergobasine) ETH-LAD LAE-32 LSA (Ergine, Lysergamide) LSD LSH LPD-824 LSM-775 Lysergic Acid 2-Butyl Amide|LSB Lysergic Acid 2,4-Dimethylazetidide Methylergometrine Methylisopropyllysergamide Methysergide MLD-41 PARGY-LAD PRO-LAD;

Phenethylamines: Aleph 2C-B 2C-B-FLY 2CBFly-NBOMe 2C-C 2C-D 2C-E 2C-F 2C-G 2C-I 2C-N 2C-O 2C-O-4 2C-P 2C-T 2C-T-2 2C-T-4 2C-T-7 2C-T-8 2C-T-9 2C-T-13 2C-T-15 2C-T-17 2C-T-21 2C-TFM 2C-YN 2CBCB-NBOMe 25B-NBOMe 25I-NBMD 25I-NBOH 25I-NBOMe 3C-E 3C-P Br-DFLY DESOXY DMMDA DMMDA-2 DOB DOC DOEF DOET DOF DOI DOM DON DOPR DOTFM Escaline Ganesha HOT-2 HOT-7 HOT-17 Isoproscaline Jimscaline Lophophine MDA MDEA MDMA MMDA MMDA-2 MMDA-3a MMDMA Macromerine Mescaline Methallylescaline Proscaline TCB-2 TFMFly TMA;

Piperazines: pFPP TMFPP;

Tryptamines: 1-Methyl-5-methoxy-diisopropyltryptamine 2,N,N-TMT 4,N,N-TMT 4-HO-5-MeO-DMT 4-Acetoxy-DET 4-Acetoxy-DIPT 4-Acetoxy-DMT 4-Acetoxy-DPT 4-Acetoxy-MiPT 4-HO-DPT 4-HO-MET 4-Propionyloxy-DMT 4-Hydroxy-N-Methyl-(a,N-trimethylene)tryptamine 5-Me-MIPT 5-N,N-TMT 5-AcO-DMT 5-MeO-2,N,N-TMT 5-MeO-4,N,N-TMT 5-MeO-a,N,N-TMT 5-MeO-a-ET 5-MeO-a-MT 5-MeO-DALT 5-MeO-DET 5-MeO-DIPT 5-MeO-DMT 5-MeO-DPT 5-MeO-EiPT 5-MeO-MET 5-MeO-MIPT 5-Methoxy-N-methyl-(a,N-trimethylene)tryptamine 7,N,N-TMT a,N,N-TMT a-ET a-MT AL-37350A Baeocystin Bufotenin DBT DET DIPT DMT DPT EiPT Ethocin Ethocybin Iprocin MET Miprocin MIPT Norbaeocystin PiPT Psilocin Psilocybin;

Others: AL-38022A Ibogaine Noribogaine Voacangine

Dissociatives

NMDAR Antagonists

Adamantanes: Amantadine Memantine Rimantadine;

Arylcyclohexylamines: Dieticyclidine Esketamine Eticyclidine Gacyclidine Ketamine Neramexane Phencyclidine Rolicyclidine Tenocyclidine Tiletamine;

Morphinans: Dextromethorphan Dextrorphan Methorphan (Racemethorphan) Morphan (Racemorphan);

Others: 2-MDP 8A-PDHQ Aptiganel Dexoxadrol Dizocilpine (MK-801) Etoxadrol Ibogaine Midafotel NEFA Nitrous Oxide Noribogaine Perzinfotel Remacemide Selfotel Xenon


Deliriants

mAChR Antagonists

3-Quinuclidinyl benzilate Atropine Benactyzine Benzatropine Benzydamine Biperiden Brompheniramine CAR-226,086 CAR-301,060 CAR-302,196 CAR-302,282 CAR-302,368 CAR-302,537 CAR-302,668 Chlorpheniramine Chloropyramine Clemastine CS-27349 Cyclizine Cyproheptadine Dicyclomine (Dicycloverine) Dimenhydrinate Diphenhydramine Ditran Doxylamine EA-3167 EA-3443 EA-3580 EA-3834 Elemicin Flavoxate Hydroxyzine Hyoscyamine Meclizine Myristicin N-Ethyl-3-piperidyl benzilate N-Methyl-3-piperidyl benzilate Pyrilamine Orphenadrine Oxybutynin Pheniramine Phenyltoloxamine Pr

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