What is a risk factor for gout? A risk factor increases your chances of developing gout but it is not certain that you will develop the disease. A risk factor is not a direct cause of the disease but the risk factors are associated in some way with developing gout.
Overweight or Obesity:
Being overweight is a risk factor for developing gout. Being overweight can lead to excess uric acid production.
Eating Purine-Rich Foods:
Eating purine-rich foods as part of your regular diet can be a risk factor for developing gout.
Excessive Alcohol Intake:
Heavy or even moderate alcohol intake can lead to hyperuricemia.
High Blood Pressure:
High blood pressure or hypertension may increase the risk for developing gout.
Lead Poisoning:
Lead poisoning can increase the risk of developing gout and is considered a risk factor.
Family History - Gender - Age:
Family history or genetics are risk factors for developing gout. Up to 18% of people with gout have a family history associated with gout. More men than women have gout. Women generally do not develop gout until they are postmenopausal. Adults develop gout more frequently than children.
Abnormal Kidney Function:
Abnormal kidney function, resulting in low urine output, can increase the risk of developing gout.
Certain Medications:
Certain medications can lead to hyperuricemia. Some of the drugs which increase the risk of developing gout include:
thiazide diuretics
low-dose aspirin and salicylates
cyclosporine
Niacin
Levodopa
Aminophylline
Medications to treat tuberculosis
Certain Medical Conditions:
Having certain medical conditions may increase the risk of developing gout. Diseases associated with an increased gout risk include:
leukemia
lymphoma
hemoglobin disorders
hypothyroidism
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