Legally sell marijuana today learn how to here!
Legally sell marijuana today learn how to here!
The article describes how cannabinoids, the active components of marijuana, inhibit tumor growth in laboratory animals and also kill cancer cells. Then it finishes off by saying that the US government has known for more than 35 years and that the media which would normally go crazy about a cancer cure story like this, doesn't at all and in fact seem to be burying the story rather than promote it in any way. I for one am amazed at the government's stance on marijuana and their failed war on drugs, which is more like a war on it's own country. I guess too many people get rich off of the war on drugs. Read the full story after the break.
by Steve Kubby, Sierra Times
November 10th, 2003
A new study published in Nature Reviews-Cancer provides an historic and detailed explanation about how THC and natural cannabinoids counteract cancer, but preserve normal cells.
The study by Manuel Guzmn of Madrid Spain found that cannabinoids, the active components of marijuana, inhibit tumor growth in laboratory animals. They do so by modulating key cell-signalling pathways, thereby inducing direct growth arrest and death of tumor cells, as well as by inhibiting the growth of blood vessels that supply the tumor.
The Guzman study is very important according to Dr. Ethan Russo , a neurologist and world authority on medical cannabis: "Cancer occurs because cells become immortalized; they fail to heed normal signals to turn off growth. A normal function of remodelling in the body requires that cells die on cue. This is called apoptosis, or programmed cell death. That process fails to work in tumors. THC promotes its reappearance so that gliomas, leukemias, melanomas and other cell types will in fact heed the signals, stop dividing, and die."
"But, that is not all," explains Dr. Russo: "The other way that tumors grow is by ensuring that they are nourished: they send out signals to promote angiogenesis, the growth of new blood vessels. Cannabinoids turn off these signals as well. It is truly incredible, and elegant."
In other words, this article explains several ways in which cannabinoids might be used to fight cancer, and, as the article says, "Cannabinoids are usually well tolerated, and do not produce the generalized toxic effects of conventional chemotherapies.
Usually, any story that even suggests the possibility of a new treatment for cancer is greeted with headlines about a "cancer cure" however remote in the future and improbable in fact it might be. But if marijuana is involved, don't expect any coverage from mainstream media, especially since mainstream editors have been quietly killing this story for the past thirty years
That's right, news about the abilility of pot to shrink tumors first surfaced, way back in 1974. Researchers at the Medical College of Virginia, who had been funded by the National Institutes of Health to find evidence that marijuana damages the immune system, found instead that THC slowed the growth of three kinds of cancer in mice lung and breast cancer, and a virus-induced leukemia.
The Washington Post reported on the 1974 study in the "Local" section on Aug. 18, 1974. Under the headline, "Cancer Curb Is Studied," it read in part: "The active chemical agent in marijuana curbs the growth of three kinds of cancer in mice and may also suppress the immunity reaction that causes rejection of organ transplants, a Medical College of Virginia team has discovered." The researchers "found that THC slowed the growth of lung cancers, breast cancers, and a virus-induced leukemia in laboratory mice, and prolonged their lives by as much as 36 percent."
"News coverage of the Madrid discovery has been virtually nonexistent in this country. The news broke quietly on Feb. 29, 2000 with a story that ran once on the UPI wire about the Nature Medicine article," complained MarijuanaNews.com editor Richard Cowan , who said he was only able to find the article through a link that appeared briefly on the Drudge Report Web page. "The New York Times, The Washington Post, and Los Angeles Times all ignored the story, even though its newsworthiness is indisputable: a benign substance occurring in nature destroys deadly brain tumors," added Cowan.
On March 29, 2001, the San Antonio Current printed a carefully researched, bombshell of a story by Raymond Cushing titled, "POT SHRINKS TUMORS; GOVERNMENT KNEW IN 74." Media coverage since then has been nonexistant, except for a copy of the story on Alternet.
It is hard to believe that the knowledge that cannabis can be used to fight cancer has been suppressed for almost thirty years , yet it seems likely that it will continue to be suppressed. Why?
According to Cowan, the answer is because it is a threat to cannabis prohibition . "If this article and its predecessors from 2000 and 1974 were the only evidence of the suppression of medical cannabis, then one might perhaps be able to rationalize it in some herniated way.
Marijuana is not a "gateway" drug that predicts or eventually leads to substance abuse, suggests a 12-year University of Pittsburgh study. Moreover, the study's findings call into question the long-held belief that has shaped prevention efforts and governmental policy for six decades and caused many a parent to panic upon discovering a bag of pot in their child's bedroom.
The Pitt researchers tracked 214 boys beginning at ages 10-12, all of whom eventually used either legal or illegal drugs. When the boys reached age 22, they were categorized into three groups: those who used only alcohol or tobacco, those who started with alcohol and tobacco and then used marijuana (gateway sequence) and those who used marijuana prior to alcohol or tobacco (reverse sequence).
Nearly a quarter of the study population who used both legal and illegal drugs at some point 28 boys exhibited the reverse pattern of using marijuana prior to alcohol or tobacco, and those individuals were no more likely to develop a substance use disorder than those who followed the traditional succession of alcohol and tobacco before illegal drugs, according to the study, which appears in this month's issue of the American Journal of Psychiatry.
"The gateway progression may be the most common pattern, but it's certainly not the only order of drug use," said Ralph E. Tarter, Ph.D., professor of pharmaceutical sciences at the University of Pittsburgh School of Pharmacy and lead author of the study. "In fact, the reverse pattern is just as accurate for predicting who might be at risk for developing a drug dependence disorder."
In addition to determining whether the gateway hypothesis was a better predictor of substance abuse than competing theories, the investigators sought to identify characteristics that distinguished users in the gateway sequence from those who took the reverse path. Out of the 35 variables they examined, only three emerged to be differentiating factors: Reverse pattern users were more likely to have lived in poor physical neighborhood environments, had more exposure to drugs in their neighborhoods and had less parental involvement as young children. Most importantly, a general inclination for deviance from sanctioned behaviors, which can become evident early in childhood, was strongly associated with all illicit drug use, whether it came in the gateway sequence, or the reverse.
While the gateway theory posits that each type of drug is associated with certain specific risk factors that cause the use of subsequent drugs, such as cigarettes or alcohol leading to marijuana, this study's findings indicate that environmental aspects have stronger influence on which type of substance is used. That is, if it's easier for a teen to get his hands on marijuana than beer, then he'll be more likely to smoke pot. This evidence supports what's known as the common liability model, an emerging theory that states the likelihood that someone will transition to the use of illegal drugs is determined not by the preceding use of a particular drug but instead by the user's individual tendencies and environmental circumstances.
"The emphasis on the drugs themselves, rather than other, more important factors that shape a person's behavior, has been detrimental to drug policy and prevention programs," Dr. Tarter said. "To become more effective in our efforts to fight drug abuse, we should devote more attention to interventions that address these issues, particularly to parenting skills that shape the child's behavior as well as peer and neighborhood environments."
Indeed, according to the study, interventions focusing on behavior modification may be more effective prevention tactics than current anti-drug initiatives. For example, providing guidance to parents particularly those in high-risk neighborhoods on how to boost their caregiving skills and foster bonding with their children, could have a measurable effect on a child's likelihood to smoke marijuana. Also, early identification of children who exhibit antisocial tendencies could allow for interventions before drug use even begins.
Although this research has significant implications for drug abuse prevention approaches, Dr. Tarter notes that the study has some limitations. First, as only male behaviors were studied, further investigation should explore if the results apply to women as well. Also, the examination of behaviors in phases beyond alcohol and marijuana consumption in the gateway series will be necessary.
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