Protein Expression
Protein expression commences after the DNA has been transcribed to messenger RNA (mRNA)
. Before the protein is synthesized and forms its structure, the mRNA are translated into polypeptide chains, without which the proteins cannot fold and synthesize.
For denoting the measurement of the presence and abundance of one or more proteins in a particular cell or tissue, proteomics researchers use Protein Expression systems. In the field of Molecular Biology, research involves a multitude of proteins and enzymes, which are required, and are synthesized for furthering research by using protein expression systems. The DNA polymerase for PCR, reverse transcriptase for RNA analysis and restriction endonucleases for cloning processes are few of the processes that are known to require assistance from the protein expression process.
The medical faculty frequently requires several proteins and non-protein coding genes for researching on various viral, bacterial, fungal parasites, yeast, baculovirus/insect, and mammalian cells as the process of gene expression is used by all known microbial life. For example, eukaryotes (including multi-cellular organisms), prokaryotes (bacteria and archaea), in which it is possibly induced by viruses for generating the macromolecular machinery for life. The study of these micro-organisms is necessary for understanding the fundamental building blocks of protein-structures, their functions, their mechanism, growth, development, and life cycles. Even non-protein coding genes such as ribosomal RNA (rRNA), transfer RNA (tRNA) or small nuclear RNA (snRNA) genes, the product is a functional RNA, which involves protein sequencing. Several steps in a gene expression process, too, require modulation such as the transcription, RNA splicing, translation, and post-translational modification of a protein.
Synthesizing a specific protein from gene strain, or validating protein sequencing of various RNA chains requires specialized protein expression systems. At Fusion Antibodies, customized solutions and equipment deliver precision results for your research be it for life sciences, biotechnology and medicine. Several routines in Protein Expression, for completing gene expression process, consist of several different steps or procedures, which may be regulated. These steps include the transcription, RNA splicing, translation, and post-translational modification of a protein.
A world leader in protein expression and purification, Fusion Antibodies is progressively assistive in accelerating your program research extensively. We can produce a recombinant protein from gene sequence in as little as 6 to 8 weeks by customizing our award-winning high throughput FET (Fusion Expression Technology) as per client requirements.
Our comprehensive service uses our high quality protein expression platform to design, analyse and produce milligram to gram quantities of purified recombinant protein such as:
Surface receptors
Transcription factors
Microbial proteins
Viral proteins
Antibodies
Biomarkers
Fusion Antibodies recombinant protein expression service is ISO 9001:2000 certified, and delivers high quality proteins that you can rely on. Our technical expertise and experience has made us the first choice of researchers from pharmaceuticals and biotech companies, national research, and world-class academic institutions. Based in the United Kingdom, our premier CRO caters to several drug development, patent pending, and Biomarker discovery projects in Europe, North America, Japan, Australia, India, China and South Korea.
by: Paul Kerr
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