Retinoic Acid Treatment Of Acne

As a cosmetic raw material and pharmaceutical raw materials

, tretinoin is now widely used, in the medical, isotretinoin is a standard method for the treatment of severe acne, is currently the most effective method of treating acne. Isotretinoin work on all aspects of acting on the incidence of acne, the treatment effect is significantly, but taking the adverse reaction into account, so try not to be used as the treatment of mild acne.

Isotretinoin is mainly used in the following situations: severe nodular cystic acne and its variant forms; associated with inflammatory acne scarring; the following therapy is no works in severe acne: use of combination therapy for the treatment of 3 months including systemic tetracyclines; acne patients with severe psychological pressure (disfigured phobia); folliculitis, gram-negative bacilli; frequent relapses need to be repeated and long-range systemic antibiotics; for some reason needs to speedy recovery. The using dose: The usual dose is 0.25-0.5mg / (kg.d), in order to reduce adverse reactions, the dose should not exceed 0.5 mg / (kg.d). Treatment depends on the patient's body weight and daily dose used. Minimum cumulative dose is use 60mg/kg as a target, but if the cumulative dose is up to 60mg/kg and didnt achieve a satisfactory effect, you can be increased to 75mg/kg. However, even if the one class acne is completely cleared, but stop using isotretinoin while have not yet reached the 60mg/kg domain value, the probability of permanent cure will be significantly reduced. There are also have the so-called shock therapy, is the first seven days of the monthly use of isotretinoin 0.5mg/kg, this method is used to complete the full course of treatment is still recurrence, prolonged course and treatment resistance in patients with acne better efficacy. Under certain conditions, such as young people with severe acne, can continuously use low-dose isotretinoin to treat these patients, but in the initial stages, the acne dissolve is poorly, but isotretinoin 10-20mg / d 4-6 month course of treatment can be quickly cleared skin lesions, and use topical tretinoin to maintain the efficacy. Not advocate large doses tretinoin, because the efficacy is not obvious, but potentially show up serious toxicity.

Before using the tretinoin systematically, it is very important to counseling and commentary for patients. Tretinoin manufacturer should be tell patients that use tretinoin can cause many adverse reactions, especially the teratogenic effects. In the first month before treating patients should be strictly contraception, until 3 months after the end of treatment should be controlled birth. If you become pregnant during treatment, and must take the abortion process. A small number of patients using the tretinoin will produce the symptoms of depression. Have a history of depression or medication of patients in the family should be careful, if show up mood swings or any symptoms of depression, should be discontinued immediately.

Other adverse reactions of the isotretinoin is drying of skin and mucous membrane. At the beginning there will be a temporary acne worse. 5% of patients will have light sensitive, joint and muscle pain, severe night blindness driving at night, severe hair loss, blood triglycerides may be elevated. Check liver function and blood lipids before the start of treatment and one month after treatment review. If there are normal, the further blood tests is no need. Long-term large doses can cause epiphyseal deformity spinal ligament calcification, osteoporosis, hyperostosis. It should be noted that isotretinoin could not use with the application tetracyclines at the same time, and could not use glucocorticoids systematically, because isotretinoin and glucocorticoids may co-induced increased intracranial pressure. Viaminate also can substitute isotretinoin, but slightly worse oral absorption, the effects show up slowly, adverse reactions is relatively mild.

Source:http://www.cosprm.com

by: anelwew

POST COMMENT

Acne Treatment Tips Therapies Stypes For Acne, Train Me Make Sure You. Find An Acne Treatment To Suit You Effectively Manage Acne Problems With These Tips Natural Treatment For Acne Breakouts Factors That Result To Adult Acne Acne Scars- How To Avoid It Clnica De Pele Com Foco Em Tratamento De Cicatrizes De Acne? Leia Mais Pensou Tratamento De Cicatrizes De Acne? Conhea Clnica De Pele Acne No More Review - See This Before You Buy! Pensou Tratamento De Cicatrizes De Acne? Conhea Clnica De Pele Four Guidelines To Find Right Acne Products Top Tips For Acne Skin Care