One interesting study is called, "Determinants of restrictive lung function in asbestos-induced pleural fibrosis" by D. A. Schwartz, J. R. Galvin, C. S. Dayton, W. Stanford, J. A. Merchant and G. W. Hunninghake - Department of Internal Medicine, University of Iowa, Iowa City 52242. J Appl Physiol 68: 1932-1937, 1990. Here is an excerpt: "We evaluated whether restrictive lung function among asbestos-exposed individuals with pleural...more
One interesting study is called, "Fibre distribution in the lungs and pleura of subjects with asbestos related diffuse pleural fibrosis." By A R Gibbs, M Stephens, D M Griffiths, B J Blight, F D Pooley - Br J Ind Med 1991;48:762-770. Here is an excerpt: "Abstract - The lungs from 13 cases of diffuse pleural fibrosis associated with a history of exposure to asbestos were examined. Samples were taken from the visceral pleura and...more
One interesting study is called, "Hemizygosity of Nf2 is associated with increased susceptibility to asbestos-induced peritoneal tumours" by Jocelyne Fleury-Feith, Céline Lecomte, Annie Renier, Mireille Matrat, Laurence Kheuang, Vincent Abramowski, Françoise Levy, Anne Janin, Marco Giovannini and Marie-Claude Jaurand - Oncogene (2003) 22, 3799–3805. Here is an excerpt: "Abstract - Biallelic NF2 gene inactivation is frequently found in human malignant mesothelioma. In order to assess whether NF2 hemizygosity may enhance susceptibility to asbestos fibres, we investigated the Nf2 status in mesothelioma developed in mice presenting a heterozygous mutation of the Nf2 gene (Nf2KO3/+), after intraperitoneal inoculation of crocidolite fibres. Asbestos-exposed Nf2KO3/+ mice developed tumoural ascites and mesothelioma at a higher frequency than their wild-type (WT) counterparts (P amosite > crocidolite. All three asbestos types were more toxic to I-407 than to ARL-6 cells. Chrysotile, amosite, and crocidolite were also tested for inhibition of colony formation in cultures of mouse colon-derived epithelial-like (MCE-1) cells; these cells were more resistant than the...more
One interesting study is called, "In vitro approaches for determining mechanisms of toxicity and carcinogenicity by asbestos in the gastrointestinal and respiratory tracts." By B T Mossman - Environ Health Perspect. 1983 November; 53: 155–161. Here is an excerpt: "Abstract Organ and cell cultures of gastrointestinal and...more
One interesting study is called, "A retrospective mortality cohort study of chrysotile asbestos products workers in Tianjin 1972–1987" by Wei-nan Cheng and Jian Kong - Environmental Research - Volume 59, Issue 1, October 1992, Pages 271-278. Here is an excerpt: "The mortality rate of a cohort of asbestos workers was investigated...more
One interesting study is called, "Asbestos-induced lung inflammation" by Marek Rola-Pleszczynski, Sylvie Gouin and Raymond Bégin - Inflammation Volume 8, Number 1, 53-62. Here is an excerpt: "Abstract - In a recently developed sheep model of progressive low-dose pulmonary exposure to asbestos, initial alveolar lymphocyte and macrophage activation was followed by pulmonary neutrophilia in higher-dose exposed animals. This was observed after 18 months of exposure to intratracheal instillations of asbestos fibers and coincided with progressive alveolitis and decreased lung compliance. Alveolar macrophages from those animals were found to produce a chemotactic factor which attracted in vitro peripheral blood neutrophils. It attracted neutrophils more efficiently from higher-exposure than lower-exposure animals. Supernatants of control macrophages exposed to asbestos in vitro were also chemotactic for PMN. Similarly, bronchoalveolar lavage fluids from the animals showed chemotactic activity for peripheral blood neutrophils. It is suggested that chronic exposure to asbestos activates alveolar macrophages to produce chemotactic factors which in turn attract neutrophils...more
One interesting study is called, "Asbestos exposure enhances the release of fibroblast growth factor by sheep alveolar macrophages." By Lemaire I, Rola-Pleszczynski M, Bégin R. - J Reticuloendothel Soc. 1983 Apr;33(4):275-85. Here is...more
One interesting study is called, "Histologic type of lung cancer and asbestos exposure" by Oscar Auerbach MD, Lawrence Garfinkel MA, Verta R. Parks BS, Alfred S. Conston MD, Vincent A. Galdi MD, Lou Jouberti,- Cancer Volume 54, Issue...more
A major landmark decision in the High Court means that hospices that care for victims of mesothelioma may be entitled to help with treatment costs. The court has ruled after a three year legal battle that a company which exposed one of its former...more
Mesothelioma is a malignant cancer which occurs in the lung due to an over limit exposure of asbestos. Asbestos is a material which is popular composition used to build a building for it can add the building's sound resistance, heat...more
Mesothelioma is a cancer that develops within the mesothelium of the body. The mesothelium is the protective covering in the body. It covers various organs, including the lungs. The mesothelium is made up of two thin layers. When cancer...more
One interesting study is called, "Radiological abnormalities among sheet-metal workers in the construction industry in the United States and Canada : relationship to asbestos exposure" - INIST Diffusion - 2, Allée du Parc de Brabois...more