Antiviral stare Avian influenza - bird flu, antiviral drugs - the pharmaceutical industry

Antiviral stare Avian influenza - bird flu, antiviral drugs - the pharmaceutical industry

Reports in various media nowadays, you can see from time to time Bird flu In the news. Because people with high demand for flu drug, Roche's production of antiviral drugs Duffy The sales climbing higher and higher. However, despite the actions of global reserves of Tamiflu sales of the drug has the potential to break through two billion U.S. dollars, but also unwilling to people of other antiviral drugs, we began to cut a striking figure in the market. Large domestic pharmaceutical companies in particular - the transfer of Roche Pharmaceutical Group received "domestic version of" successful listing of Tamiflu, the influenza drug market in China will bring about remarkable changes in the structure.

According to market Research Institutions by Datamonitor, a research company that in the long run, treatment of respiratory syncytial virus (RSV) antiviral drugs and Vaccine May gradually to the current priority treatment in the field of therapeutic challenge. The focus therapeutic areas Package Including herpes simplex virus / varicella zoster virus (HSV / VZVs) and cytomegalovirus (CMVs). Three companies dominate

Long time, the treatment of herpes and respiratory antiviral market has been from Europe Pharmacy Company GlaxoSmithKline , Dominated by Roche and Novartis. In 2004, the three company's total sales accounted for the market share of 86%. However, three relatively limited competition between the companies, including GlaxoSmithKline in the HSV / VZV dominant therapeutic areas, Roche CMV treatment in the market dominating position. Novartis Although HSV / VZV therapeutic areas lighter weight, but it is likely through the introduction of drugs A-60444 in the RSV antiviral market leading position. A-60444 is being developed by Novartis and the British biotechnology company Arrow to develop small molecule HIV suppression Preparation .

In the treatment of Infectious disease (ID), and respiratory diseases, herpes antiviral market, GlaxoSmithKline are leading. In 1981, GlaxoSmithKline launched ganciclovir (Zovirax / Shu Wei therapy), the HSV / VZV treatment on the market first established his position. However, as Shu Wei treatment in the last century to lose patent protection of 90 years, the company also suffered a major blow, because at that time, Shu Wei treatment are blockbuster drugs has become one of GSK earnings important source of. However, GlaxoSmithKline has launched the 1995 follow-up of drug valaciclovir (Valtrex / Wei Desi). After listing the drug quickly became the market leader, which partly offset the patent invalid because Shu Wei treatment caused the loss. In 2004, Wei Desi rose to blockbuster drugs, with sales of 10 billion U.S. dollars. In the treatment of respiratory diseases, herpes and antiviral market, it holds a 50% share.

Order to establish and maintain their treatment in the CMV market leader, Roche in the product life cycle management has taken effective approach. Rose started to enter this market is in its acquisition of Syntex Pharmaceuticals, the company immediately introduced in 1994 to treat CMV antiviral drugs ganciclovir (Cytovene / Cymevene). As with GlaxoSmithKline, Roche in the drug in 2002 and 2005 in succession to lose patent protection between the occasion of the launch of the follow-up product valganciclovir (Valcyte / million Zevi), to deal with generic competition, to prevent the Pharmaceutical sales fell for.

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