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Blastocyst Culture A New Approach To Give Birth To A Child

Blastocyst is an embryo that develops after five to seven days of fertilization

. It is a thin-walled hollow structure in early embryonic development. It contains cluster of cells called the inner cell mass. The outer layer of the cell gives rise to the supporting tissues for the uterus while the inner gives rise to the tissues of the body.

Blastocyst culture is a selection of the best quality embryos for the transfer to the uterus of the mother. The quality of the embryo is very important for the couple who are experiencing infertility. As Blastocyst culture transfers selected embryos to the uterus of the mother the risk of multiple pregnancy reduces and so the danger of miscarriage keeping overall pregnancy rates high.

After few days the cell in the Blastocyst starts differentiating. The differentiation which cannot be seen in the early Blastocyst with small cavity can be visualised properly by now. Just under the outer shell the surface cells that surround the cavity are called the trophectoderm. The cells which are at the centre of the group of cells are called the inner cells mass which later form into foetus.

Advantages and Disadvantages of the Blastocyst culture


Normally two to three day old embryo are normally found in the fallopian tube and not in the uterus. After ovulation the first uterus moves into the uterus for approx 80 hours. As embryo implantation process begin Blastocyst formation and hatching out of the embryonic shell occurs within 3 days. The chances of transfer of Blastocyst embryo can be done in five days if healthy Blastocyst forms at a high rate. By Blastocyst culturing if we realise that some of them have not become Blastocyst we always have an opportunity to choose the most best embryo to transfer. So even if the rates of the embryo are less but the quality is great then yet there are chances of obtaining high pregnancy success rates

If this 5embryo Blastocyst transfer is delayed even little bit then the chances of the high quality goes down. Therefore if the quality control and the test culture system is in the IVF lab is not proper then the output of the test will not be obtained properly. The embryos should be stored properly before they enter the weak culture.

The ultimate goal of the Blastocyst culture is to provide high quality embryo giving it a result in live birth if the child

by: Dr. Anoop Gupta
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Blastocyst Culture A New Approach To Give Birth To A Child