clone cancer new test detection works
clone cancer new test detection works
clone cancer new test detection works
Test friends consumer study; Results of DNA helps risk prediction
- a test new, consumer-friendly for colon cancer, once adopted, could convince more Americans to undergo screening for fatal cancer according to the researchers who present their conclusions on the effectiveness of the test in a Conference on cancer in Philadelphia.
At the same meeting, researchers reported that they have new clues about how the characteristics of DNA can help predict the risk of colon cancer.
The research was presented at the American Association for the Special Conference on research on cancer, colorectal cancer: biology to therapy.
One of each 17 of us shall colorectal cancer in our lives, "said David Ahlquist, MD, Professor of medicine and a consultant in Gastroenterology Clinic may in Rochester, Minn.., who presented his findings on the new colorectal cancer screening test."
Colon cancer is the second cause of death by cancer among men and women in the United States, many adults not undergo tests one time arrive at age 50 (or earlier for those with a family history), Ahlquist said at a news conference.
Estimates of how many adults are subjected to tests vary, but Ahlquist says probably only 40% adhere to the schedule of the projection in time.
A screening colonoscopy, which inserts a flexible tube, illuminated with a video camera to examine the colon test requires dietary restriction and preparation of patients colon.Los must often take time off and need transport commencement of the procedure.
The new test, a next generation known as proof of methylation of DNA stool test detects specific tumor or methylations alterations in DNA in cells in the stools of cancerous lesions shed or precancerosas.La test can be done at home without restrictions in the diet or bowel preparation.
"At the meeting, Ahlquist presented the results of the first study of 1,100 patients clinical evaluation."We were satisfied with the results of this first clinical study, said."
Proof lies pre-cancerous tumors that were larger than a centimeter (less than a half inch) and 85% of cancers found 64%.
"Ahlquist called figure of 85%"very high"and adds:"It would be very difficult to find an approach to non-invasive that could obtain that range."
"The test also find tumors on both sides of the colon, Ahlquist says, a feat which is not always achieved through colonoscopy.""These results are encouraging," said.
The detection rate was 87% of all cancers in stages I to III, considered the most curable and 69 per cent for phase IV, the most advanced.
"Test is better at detecting cancer early, says, because cells may be less methylated in stages posteriores.El testing approach is to detect cancer early, says.""We are destined for early stage cancers, and that is where the test is best."
The median age of patients was 60 (half were older, younger half).
Positive test results would be with colonoscopy.
A clinical trial of new stool test is expected to start in 2011, says, and if all goes well the test might be available soon thereafter.
Ahlquist, and clinical Mayo are working in collaboration with Corp.Madison, Wisconsin, exact sciences to develop the test
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