Mesothelioma is a lethal cancer that can attack the membranes surrounding the heart, lung, and stomach. One interesting article that examines asbestos exposure in vitro is called, Human Alveolar Macrophage Cytokine Release in Response to in Vitro and in Vivo Asbestos Exposure by Raymond C. Perkins, Ronald K. Scheule1, Raymond Hamilton, Glen Gomes, Gary Freidman and Andrij Holian - Division of Pulmonary and Critical Care Medicine, Departments of...more
As many are already aware, asbestos exposure has been linked to a number of life threatening diseases. Most exposure related illnesses result from the inhalation of tiny asbestos particles or fibers. One interesting study that examined the rate of disease in miners is called, Relation between asbestosis and bronchial cancer in amphibole asbestos miners by G K Sluis-Cremer, B N Bezuidenhout - Br J Ind Med 1989;46:537-540 - Epidemiology Research...more
People that have worked within the asbestos industry or where the mineral was used in that products they handled are generally at higher risk for developing cancer and mesothelioma. One interesting study that examines the advantage of bleach digestions is called, A procedure for the isolation of amosite asbestos and ferruginous bodies from lung tissue and sputum by Marion G. Williams Jr. a; Ronald F. Dodson b; Carolyn Corn a;George A. Hurst - Journal of Toxicology and Environmental Health, Part A, Volume 10, Issue 4 & 5 October 1982 , pages 627 638. Here is an excerpt: Abstract - A comprehensive scheme is described for isolating amosite asbestos and ferruginous bodies from fixed and unfixed human lung tissue and sputum. This qualitative procedure avoids many of the problems associated with previous isolation techniques and illustrates the advantages of brief bleach digestions. The samples are digested in prefiltered Wright laundry bleach (9.2% sodium hypochlorite), collected on 0.2-m Nuclepore filters by vacuum filtration, rinsed with distilled water and absolute ethanol, and examined visually for excessive residue. If organic residues are suspected or are known to occur, the...more
Important info about Mesothelioma By: MUHAMMAD FARHAN SIDDIQUI About the Author Siddiqui Arsalan is student of medical college and it is his hobby to read and write about different types of diseases.For more informations and my source:http://infopakistan.page.tl/MESOTHELIOMA.htm (ArticlesBase SC #2917643) ...more
Conclusions - Foscan-mediated PDT can be safely combined with surgery at the established MTD. Unlike most other surgery-based multimodal treatments for mesothelioma, Foscan-mediated PDT affords the option, in selected patients, of accomplishing tumor debulking with a lung-sparing procedure rather than an extrapleural pneumonectomy. A phase II study...more
Another interesting study is called, "Combination raltitrexed (Tomudex(R))-oxaliplatin: a step forward in the struggle against mesothelioma? The Institut Gustave Roussy experience with chemotherapy and chemo-immunotherapy in mesothelioma." By Fizazi K, Caliandro R, Soulié P, Fandi A, Daniel C, Bedin A, Doubre H, Viala J, Rodier J, Trandafir L, Le Chevalier T, Cvitkovic E, Armand J, Ruffié P - Eur J Cancer. 2000 Aug;36(12):1514-21. Here is an excerpt: "Abstract - The aim of this study was to review the experience of the Institut Gustave Roussy in 163 patients with malignant mesothelioma over a 9-year period. Data from seven consecutive prospective trials, four of chemo-immunotherapy and three of chemotherapy were reviewed. The rationale, methods and results of these trials are summarised and discussed. 98 patients were included in four phase II trials of chemo-immunotherapy whose common denominator was a combination of cisplatin and alpha-interferon. The response rate ranged from 15% to 40%. High-dose weekly cisplatin combined with alpha-interferon yielded the highest response rate but the toxicity of this regimen was considered unacceptable. Neither higher doses of...more
Conclusions - Integrated computed tomography-positron emission tomography increases the accuracy of malignant pleural mesothelioma staging and is important in determining the appropriate therapy in patients being considered for extrapleural...more
Conclusions: SS1P is well tolerated with pleuritis as the DLT at the highest dose level. Evidence of clinical activity was noted in a group of heavily pretreated patients. Phase II clinical trials of SS1P are being planned for malignant mesothelioma...more
When STAV serum-free conditioned medium was separated by using fast protein liquid chromatography Superose 6 gel filtration, two motility-inducing protein peaks were detected. The first peak contained proteins with molecular weight > 220,000 that had...more
Another interesting study is called, "Anti-MOC-31: a potential addition to the pulmonary adenocarcinoma versus mesothelioma immunohistochemistry panel." By Sosolik RC, McGaughy VR, De Young BR. - Department of Pathology, Ohio State University Medical...more
If a settlement isn't reached the case will go to trial. Both sides will present their evidence and testimony during the trial. Once the trial is concluded the jury will decide the outcome of your case.Mesothelioma Lawsuits - Fight for What You...more
Asbestos exposure is an impetus for disease development, its carcinogenicity for the mesothelium and lung tissue is well documented. One interesting study that examines this issue is called, Silica, asbestos, man-made mineral fibers, and cancer by...more