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What Is Revealed By The Human Mitochondrial Sequence?

What Is Revealed By The Human Mitochondrial Sequence

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The human mitochondrial DNA sequence is passed down exclusively from mother to child. It serves as an unbroken familial line down through generations, connecting relatives near and far with more unique patterns and pairing than the naked eye can see. Revealed only under an electron microscope, the human mitochondrial sequence is a special signature of who you are and where you came from.

Sequencing is usually done by forensic researchers looking to trace ancestral connections. It does not work for paternity issues, as the strains are passed down exclusively from mothers. In this way, it stays out of courtrooms unless being used for adoption records or for fossil reclamations. The majority of the time, mitochondrial sequencing will be done purely to prove research theories or to trace genetic disorders.

While it cannot be used as a perfect predictive tool, it can be used to assess the genetic disposition of a body for a kind of inherited disease. It may not be able to say when you too might show symptoms of a family ailment, but it would be able to say whether or not you had the same sequencing as another sufferer in your family. You can obtain these kinds of sequencing results from private laboratories or upon referral by your regular doctor.


Those who are interested in using mitochondrial sequencing to trace their family trees may find it to be an expensive but useful tool. Generally, the closer the match up of the DNA sequencing, the more closely related two individuals are to each other. In this way, kinship bonds between branches of families can be proven, even if the families have lived in different countries for years.

Science is continuing to explore additional uses for the technology. The work of the mitochondria at the cellular level makes these organelles vitally important, but they aren't perfectly understood. Millions of dollars in grant money each year go into projects that are trying to make the tiny mitochondria more clear to scientists, diagnosticians, and researchers. Since the pattern is strong and stable, there may be many more things that this chain of DNA molecules could be telling you and your doctor about your health, your past, and your future.
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